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The present study investigates properties of heat-induced, self-standing gels of globular proteins. Native egg white protein (EWP) with 9,8 wt% protein and 0,395 wt% NaCl content was adjusted to pH = 7,0 and heated from 25 to 85 °C via Ohmic heating (OH) and conventional heating (COV) with respective come-up times (CUT, 240 and 1200 s) and holding times (HOLD, 30 and 900 s). Gels heated under OH showed lower denaturation levels and less water holding capacity. When HOLD was short, the firmness of OH gels exceeded COV gel firmness but deceeded at long HOLD. Similarly, at short HOLD OH samples presented higher hydrophobic interactions whereas at long HOLD COV gels showed more hydrophobic interactions. This correlated with changes of intermolecular beta-sheet structures which increased with HOLD at COV but decreased or remained unchanged during OH. Furthermore, as an SDS-PAGE revealed the main EWP, ovalbumin, did not fully denature when heated via OH, this lead to the assumption that the oscillatory electric field partially interferes the complete denaturation and development of intermolecular beta-sheet structures and hydrophobic interactions during thermal gelation of this protein. Scanning electron microscopy also showed deviances in network structures between OH and COV as COV gels exhibited a denser and OH gels a more open and porous network structure.
Currently, the modelling of drying processes of plant tissues pre-treated by pulsed electric field (PEF) is following experimentally identified curves or separate heat and mass transfer and diffusion models with different levels of accuracy. This research had two major objectives: mathematical modeling and control of drying process of different vegetables pretreated by PEF during convective drying. The mathematical modeling was based on Luikov's heat and mass transfer model along with properties of different vegetables. Computer modelling was done using the difference method for predicting moisture and the temperature potentials of untreated and PEF-treated vegetables. The formulation and the solution procedures were applied to simulate the simultaneous heat and mass transfer in selected vegetables subjected to the convective drying. Suggested model had a good correlation with experimental results. Moreover, cell disintegration index can be used as a controllable parameter in heat and mass transfer models to predict drying behavior of potato, onion, and carrot tissues. Obtained drying models can be used as a mathematical tool to predict drying behavior for various types of agricultural products pre-treated by pulsed electric field.
The impact of Pulsed Electric Fields (PEF) on the peeling ability of different fruits and vegetables in particular tomatoes, peaches, peppers, and oranges were investigated. Samples were exposed to a fixed electric field strength of 2.15 kV/cm. The specific energy ranged from 0.6 kJ/kg to 50.3 kJ/kg. The treated raw materials were analysed regarding to the peeling ability, skin size and weight and firmness. The best result for tomatoes at a specific energy of 1.2 kJ/kg induced a high score of peeling ability that led to less product loss and could therefore increase the yield by 33.84%–41.53% compared to untreated samples. Moreover, an increased skin size by a factor of 3.7 was observed. However, PEF had no significant impact on peeling ability of oranges, peppers, and peaches. Although oranges showed an improvement in peeling ability by up to 32%, this cannot be traced back to the PEF treatment. The different properties and structures of the raw materials were discussed and provided indications about the limitation of PEF.
Background
Spinach is a nitrogen (N) demanding crop with a weekly N uptake of up to 60 kg ha–1. Consequently, a high N supply is required, which can temporarily lead to high quantities of nitrate (NO3–) being at risk of leaching.
Aims
The objective of this study was to develop a N fertilization approach to reduce the risk of NO3– leaching in field-grown spinach production without adversely affecting crop yield and quality at an early and late harvest stage.
Methods
Ten fertilization trials were conducted to compare different base fertilization rates and splits of top dressings. For top dressings, granulated fertilizers or foliar sprays were used. In a further treatment, N supply was reduced by withholding the second top dressing of 50–70 kg ha−1.
Results
Nitrate concentration at risk of leaching was considerably reduced by decreasing the base fertilizer rate as well as by splitting the top dressing. However, at an early harvest stage, total aboveground dry mass was reduced by, on average, 6% by these measures across all seasons. In contrast, at a later harvest stage, spinach was less affected by the fertilizer schedule. Urea foliar sprays proved to be insufficient in promoting plant growth and caused leaf necrosis. A reduced N supply led to impaired plant growth and yellowish leaves in both spring and winter.
Conclusions
Base N fertilization of spinach is only required in spring, but not in other seasons. Despite slight yield reduction, the top dressing should be split to reduce the risk of NO3− leaching after an early harvest.
Intensive care units (ICU) are often overflooded with alarms from monitoring devices which constitutes a hazard to both staff and patients. To date, the suggested solutions to excessive monitoring alarms have remained on a research level. We aimed to identify patient characteristics that affect the ICU alarm rate with the goal of proposing a straightforward solution that can easily be implemented in ICUs. Alarm logs from eight adult ICUs of a tertiary care university-hospital in Berlin, Germany were retrospectively collected between September 2019 and March 2021. Adult patients admitted to the ICU with at least 24 h of continuous alarm logs were included in the study. The sum of alarms per patient per day was calculated. The median was 119. A total of 26,890 observations from 3205 patients were included. 23 variables were extracted from patients' electronic health records (EHR) and a multivariable logistic regression was performed to evaluate the association of patient characteristics and alarm rates. Invasive blood pressure monitoring (adjusted odds ratio (aOR) 4.68, 95%CI 4.15–5.29, p < 0.001), invasive mechanical ventilation (aOR 1.24, 95%CI 1.16–1.32, p < 0.001), heart failure (aOR 1.26, 95%CI 1.19–1.35, p < 0.001), chronic renal failure (aOR 1.18, 95%CI 1.10–1.27, p < 0.001), hypertension (aOR 1.19, 95%CI 1.13–1.26, p < 0.001), high RASS (aOR 1.22, 95%CI 1.18–1.25, p < 0.001) and scheduled surgical admission (aOR 1.22, 95%CI 1.13–1.32, p < 0.001) were significantly associated with a high alarm rate. Our study suggests that patient-specific alarm management should be integrated in the clinical routine of ICUs. To reduce the overall alarm load, particular attention regarding alarm management should be paid to patients with invasive blood pressure monitoring, invasive mechanical ventilation, heart failure, chronic renal failure, hypertension, high RASS or scheduled surgical admission since they are more likely to have a high contribution to noise pollution, alarm fatigue and hence compromised patient safety in ICUs.
Einfluss einer Selen-Biofortifikation auf verschiedene Qualitätsparameter von Äpfeln (Abstract)
(2022)
Background
To detect changes in biological processes, samples are often studied at several time points. We examined expression data measured at different developmental stages, or more broadly, historical data. Hence, the main assumption of our proposed methodology was the independence between the examined samples over time. In addition, however, the examinations were clustered at each time point by measuring littermates from relatively few mother mice at each developmental stage. As each examination was lethal, we had an independent data structure over the entire history, but a dependent data structure at a particular time point. Over the course of these historical data, we wanted to identify abrupt changes in the parameter of interest - change points.
Results
In this study, we demonstrated the application of generalized hypothesis testing using a linear mixed effects model as a possible method to detect change points. The coefficients from the linear mixed model were used in multiple contrast tests and the effect estimates were visualized with their respective simultaneous confidence intervals. The latter were used to determine the change point(s). In small simulation studies, we modelled different courses with abrupt changes and compared the influence of different contrast matrices. We found two contrasts, both capable of answering different research questions in change point detection: The Sequen contrast to detect individual change points and the McDermott contrast to find change points due to overall progression. We provide the R code for direct use with provided examples. The applicability of those tests for real experimental data was shown with in-vivo data from a preclinical study.
Conclusion
Simultaneous confidence intervals estimated by multiple contrast tests using the model fit from a linear mixed model were capable to determine change points in clustered expression data. The confidence intervals directly delivered interpretable effect estimates representing the strength of the potential change point. Hence, scientists can define biologically relevant threshold of effect strength depending on their research question. We found two rarely used contrasts best fitted for detection of a possible change point: the Sequen and McDermott contrasts.
Background: New ischaemic brain lesions on magnetic resonance imaging (MRI) are reported in up to 86% of patients after transcatheter edge-to-edge repair of the mitral valve (TEER-MV). Knowledge of the exact procedural step(s) that carry the highest risk for cerebral embolisation may help to further improve the procedure.
Aims: The aim of this study was to identify the procedural step(s) that are associated with an increased risk of cerebral embolisation during TEER-MV with the MitraClip system. Furthermore, the risk of overt stroke and silent brain ischaemia after TEER-MV was assessed.
Methods: In this prospective, pre-specified observational study, all patients underwent continuous transcranial Doppler examination during TEER-MV to detect microembolic signals (MES). MES were assigned to specific procedural steps: (1) transseptal puncture and placement of the guide, (2) advancing and adjustment of the clip in the left atrium, (3) device interaction with the MV, and (4) removal of the clip delivery system and the guide. Neurological examination using the National Institutes of Health Stroke Scale (NIHSS) and cerebral MRI were performed before and after TEER-MV.
Results: Fifty-four patients were included. The number of MES differed significantly between the procedural steps with the highest numbers observed during device interaction with the MV. Mild neurological deterioration (NIHSS ≤3) occurred in 9/54 patients. New ischaemic lesions were detected in 21/24 patients who underwent MRI. Larger infarct volume was significantly associated with neurological deterioration.
Conclusions: Cerebral embolisation is immanent to TEER-MV and predominantly occurs during device interaction with the MV. Improvements to the procedure may focus on this procedural step.
The apple fruit (Malus domestica L. Borkh) is one of the most popular fruits worldwide. Beyond their beneficial properties, apples contain proteins that trigger allergic reactions in susceptible consumers. Mal d1 to d4 are allergens present in a variety of different isoforms in apples. In this study, we used proteomics to quantify all four Mal d proteins in 52 apple genotypes with varying allergenic potentials. A total of 195, 17, 14, and 18 peptides were found to be related to Mal d1, d2, d3, and d4 proteins, respectively of which 25 different Mal d proteins could be unambiguously identified. The allergenic potential of the Mal d isoforms was characterized by comparing the isoform abundance with the allergenic score of genotypes from oral challenge tests. The detected Mal d peptides presumably have different IgE binding properties and could be used as potential molecular markers to discriminate between hypoallergenic and hyperallergenic cultivars.
Currently, only non-imaging chlorophyll fluorescence measurements are used to identify the Lower Oxygen Limit (LOL) in Dynamic Controlled Atmosphere - Chlorophyll Fluorescence (DCA-CF) storage. The disadvantage of non-imaging fluorescence is that no statement can be made about the spatial heterogeneity of the sample. In contrast, chlorophyll fluorescence imaging can detect spatial heterogeneity of photosynthetic activity and has been established in research for some decades because the information benefit is higher. In this study, the chlorophyll fluorescence (Fo, Fm, Fv, Fv/Fm) of apples (Malus x domestica, BORKH.) was measured with a fluorescence imaging system in situ during storage. Intact apples of ‘Braeburn’ and ‘Golden Delicious’ were stored under low-oxygen stress conditions (< 1 kPa). The metabolic shift from aerobic to fermentative metabolism was made visible with the chlorophyll fluorescence imaging and was spatially localized on the sample. Furthermore, a method was developed to identify the LOL based on the chlorophyll fluorescence imaging combined with the histogram division method. This method considers the heterogeneity of the fluorescence and bundles the measured Fo data as histograms. Our results showed that the fluorescence imaging combined with the histogram division method can be a powerful tool for identifying the LOL.
Trotz wachsender Bedeutung von Talent Management (TM) in Unternehmen gelingt es nicht, der Talentknappheit zu begegnen. Die Corona-Pandemie verschärft die Situation. Denn der bislang nicht ausgeschöpfte Anteil qualifizierter Frauen auf dem Arbeitsmarkt wächst u. a., weil sich anteilig mehr Frauen als Männer zur Erfüllung von Sorgeaufgaben vom Arbeitsmarkt zurückziehen. Gleichzeitig werden Maßnahmen zur Vereinbarung von Berufs- und Privatleben bislang bei der Rekrutierung und Bindung von Talenten nicht oder unzureichend thematisiert. Auf der Basis der wissenschaftlichen Diskussion wird daher die Frage untersucht, inwiefern sich Vereinbarkeitsangebote von Talenten karriereunschädlich nutzen lassen.
Der Umgang mit Veränderungsprozessen ist zum festen Bestandteil des Arbeitsalltags geworden. Irgendetwas wird immer verändert, seien es Arbeitsaufgaben, Technologien, Geschäftsprozesse, Strukturen oder auch die Kultur einer Organisation. Man möchte hierdurch die Produktivität steigern, Bürokratie abbauen, die Wettbewerbsfähigkeit verbessern, Qualität bzw. Innovationen fördern und vieles mehr. Inwieweit man diese Ziele auch erreicht, hängt sehr stark davon ab, ob der Wandel auf breiter Basis akzeptiert und unterstützt wird. Führungskräfte und Verantwortliche für Change-Projekte, Organisations- oder Führungskräfteentwicklung können als „Change Leader“ durch die Art, wie sie führen, entscheidend zum Gelingen beitragen. Das Führen in Veränderungsprozessen wird in diesem Ratgeber entlang von sechs Handlungsfeldern strukturiert: (1) Individuelle Reaktionen Change-Betroffener verstehen, (2) Potenziale von Achtsamkeit in Veränderungsprozessen nutzen, (3) den Wandel klug organisieren, (4) wertschätzend handeln, (5) Verhaltensänderung unterstützen und (6) Kreativität fördern. Die Kapitel sind handlungsorientiert strukturiert und berücksichtigen Erkenntnisse aus der psychologischen Forschung. Reflexionsfragen, Checklisten, Arbeitsblätter und Übungen am Ende jedes Kapitels regen zur Reflexion der Inhalte an und unterstützen den Transfer in die Praxis.
Warum sind Erziehungshilfen ein verbreiteter Teil der Schulorganisation? Was unterscheidet, verbindet aber auch die schulische und außerschulische Erziehungshilfe? Und wie könnte eine bedarfsgerechte, die individuelle Förderung der jungen Menschen unterstützende, Familien stärkende und die sozialräumliche Vernetzung voranbringende Kooperation zwischen Schulen und Erziehungshilfe aussehen? Diesen Fragen widmet sich dieses Buch ausgehend von lebensweltlichen Perspektiven junger Menschen in einer sehr grundlegenden Weise. Dabei werden nicht nur die Anlässe, Erscheinungsformen und Bedingungen der Arbeitsbündnisse von Schule und Erziehungshilfe erörtert, sondern auch ein neu gewichtetes und innovative Gestaltungsmöglichkeiten eröffnendes Verständnis von Schule und Erziehungshilfe.
Artificial intelligence (AI) and human-machine interaction (HMI) are two keywords that usually do not fit embedded applications. Within the steps needed before applying AI to solve a specific task, HMI is usually missing during the AI architecture design and the training of an AI model. The human-in-the-loop concept is prevalent in all other steps of developing AI, from data analysis via data selection and cleaning to performance evaluation. During AI architecture design, HMI can immediately highlight unproductive layers of the architecture so that lightweight network architecture for embedded applications can be created easily. We show that by using this HMI, users can instantly distinguish which AI architecture should be trained and evaluated first since a high accuracy on the task could be expected. This approach reduces the resources needed for AI development by avoiding training and evaluating AI architectures with unproductive layers and leads to lightweight AI architectures. These resulting lightweight AI architectures will enable HMI while running the AI on an edge device. By enabling HMI during an AI uses inference, we will introduce the AI-in-the-loop concept that combines AI's and humans' strengths. In our AI-in-the-loop approach, the AI remains the working horse and primarily solves the task. If the AI is unsure whether its inference solves the task correctly, it asks the user to use an appropriate HMI. Consequently, AI will become available in many applications soon since HMI will make AI more reliable and explainable.
Zukünftige Nonprofit-Manager*innen sind mit komplexen Herausforderungen in einem sich stetig wandelnden Umfeld konfrontiert. Themen wie Klimaschutz, soziale Ungleichheit oder auch Demokratieförderung haben einen starken Einfluss auf die Arbeitsfelder der Nonprofit-Organisationen. Eine zentrale Aufgabe der Führungskräfte ist daher in dieser Komplexität konstruktiv agieren zu können. Dafür sind Kompetenzen erforderlich: Ganz zentral ist die Fähigkeit, sich initiativ und eigenverantwortlich mit den Herausforderungen unserer Zeit auseinanderzusetzen und im besten Fall geeignete Lösungen dafür zu finden sowie diese zielführend kommunizieren zu können. Aus diesem Grund wird genau diese Fähigkeit bei Studierenden aus den Masterstudiengängen Management in Nonprofit-Organisationen und Soziale Arbeit der Hochschule Osnabrück gefördert. Im Rahmen des Moduls Handlungsfelder II entwickelten rund 30 Studierende im Wintersemester 2022/2023 in einer Denkwerkstatt Forschungsergebnisse und Lösungsideen zum Thema „Osnabrück 2030 – Demokratie leben“. Die Studierenden wählten in einem partizipativen Prozess ihre eigenen Schwerpunktthemen wie zum Beispiel Mobilität oder Bildung aus und arbeiteten dann ein Semester lang an den Inhalten. Bei der Erarbeitung wurden sie durch Marlene Eimterbäumer begleitet, die Modelle, Methoden und Coaching zur Unterstützung bereit stellte. Die Modelle und Methoden finden sich teilweise in den Beiträgen der Studierenden wieder (unter anderem das Social Ecological Model und der Business Model Canvas). Am Ende des Semesters stand eine Präsentation vor den Kommiliton*innen, der Lehrenden und auch vor externen Gästen, die aus unterschiedlichen Expertisegebieten im Themenbereich „Demokratie“ kamen und dementsprechend Feedback aus der Praxis geben konnten. Das Modul selbst wurde von der Hochschule im Rahmen der Innovativen Lehre an der Fakultät Wirtschafts- und Sozialwissenschaften gefördert. Für die Studierenden stellte das Modul durchaus eine Herausforderung dar, denn in der Denkwerkstatt musste unter hoher Komplexität stark prozessbezogen gearbeitet werden im Gegensatz zu der sonstigen hohen Ergebnisorientierung. Die durchweg sehr guten Ergebnisse zeigen, dass der Einsatz und die kontinuierliche Kommunikation und Zusammenarbeit sich gelohnt haben. Aufgeteilt ist das vorliegende Buch in die fünf Themen: Wahlen, Partizipation, Partizipative Raumentwicklung, Politische Bildung und Medienkompetenz. Zu diesen Themen finden Sie jeweils erst einen Beitrag der Forscher*innen und darauffolgend einen Beitrag zur Darstellung einer Lösungsidee.
Besides yield reduction weeds have positive effects, like enhancing biodiversity or reducing soil erosion. The aim of the work is to enhance biodiversity without yield losses. In growing season 2021/22 a field experiment with winter triticale was conducted to experience the impact of mechanical weed control, sowing date and sowing rate. Especially hoeing had a positive impact on vegetative growth and grain yield while weed growth was inhibited but weed biodiversity stayed equal or increased. A lower seed rate or an earlier sowing date made in general no difference at flowering or harvesting stage.
Um die Ausgaben der gesetzlichen Krankenversicherung in Deutschland zu senken, wurde mit dem GKV-Finanzstabilisierungsgesetz neben anderen Maßnahmen die Aufhebung der Neupatientenregelung zum Jahresbeginn 2023 durchgesetzt. In politischen Kreisen wurde die Aufhebung der Regelung unter Verweis auf einen erschwerten Patientenzugang im ambulanten Sektor teils deutlich kritisiert. Um zu überprüfen, wie es um die Bereitschaft zur Aufnahme von Neupatienten nach Aufhebung der Neupatientenregelung bestellt ist, wurden im Rahmen einer randomisierten empirischen Feldstudie im Zeitraum von März bis April 2023 insgesamt 180 niedersächsische Hausärzte angerufen. Dabei gab sich der Studienautor als zugezogener Neupatient aus, der auf der Suche nach einem neuen Hausarzt sei. Da im Vorfeld eine schlechte telefonische Erreichbarkeit erwartet worden war, wurden jeder Arztpraxis bis zu drei Anrufversuche gewährt. Es zeigte sich, dass gut zwei Drittel der erreichten Praxen zur Aufnahme eines Neupatienten bereit sind. Außerdem konnte festgestellt werden, dass ein hoher regionaler Versorgungsgrad mit einer schlechten telefonischen Erreichbarkeit der Arztpraxen in Verbindung steht. Bezüglich der Organisationsformen und der Anzahl an Ärzten je Praxis konnten keine signifikanten Korrelationen festgestellt werden. Montags war die telefonische Erreichbarkeit der Praxen deutlich geringer als mittwochs und freitags. Die vorliegende Bachelorarbeit beschreibt die für die Studiendurchführung relevanten Grundlagen der hausärztlichen Versorgung in Deutschland, begründet die verwendete Methodik und diskutiert die Studienergebnisse.
Bamboo is an environmentally friendly alternative to conventional materials in mechanical engineering such as steel or aluminium. Bamboo is the fastest growing plant in the world. Instead of releasing CO2 during the manufacturing process, bamboo absorbs CO2 as it grows.
In addition to the sustainability aspect, bamboo tubes also offer excellent properties as a lightweight construction material, which have been optimised through evolution. Bamboo tubes have high strength and stiffness at low weight when used as tension-compression bars or bending beams. Bamboo has strong, high-density fibres at the boundary area, where bending stresses are greatest. Towards the inside, where the stresses are lower, the bamboo becomes porous to optimise weight. This, together with knots arranged in regular intervals, counteracts buckling.
In mobile applications such as cars and bicycles, lightweight construction is sought for energy efficiency reasons. Because of its excellent lightweight properties, the project investigated whether bamboo could be used in mobile, automotive or agricultural engineering. For example, a bamboo bicycle frame has been developed with the aim to be as light as possible. There are bamboo bicycles on the market, but they can only be made one at a time by hand. The bamboo tubes are joined together and functional elements such as the bottom bracket and headset are integrated by wrapping them in resin-impregnated natural or carbon fibres. This makes the joints very heavy. A different approach is taken here: the bamboo tubes are drilled out slightly to achieve a defined internal diameter, and then short aluminium tubes are glued into the bamboo canes from the inside. To prevent the cane from breaking in the circumferential direction, i.e. perpendicular to the fibre direction, the bamboo tubes are wrapped in a thin layer of natural or carbon fibre impregnated with synthetic resin. The aluminium tubes and functional elements are welded or soldered together beforehand.
The design of the bicycle frame, i.e. the dimensioning of the bamboo tubes and joints, was based on extensive bending and tensile tests to determine the strength properties of the natural material bamboo. The bonding between the bamboo cane and the aluminium tube was also investigated experimentally. Finally, several prototype bicycle frames were made and tested for durability according to DIN-EN-14764. The frames passed the tests.
The result is a bamboo bicycle that is manufactured with standardised connectors and joints. The assembly concept developed allows both fully automated and semi-automated series production of bamboo bicycles.
Biomechanical analyses are capable of capturing and evaluating human motions. In addition to the major biomechanical fields of kinetics and kinematics, electromyography (EMG) provides a reliable way to analyse neuromuscular activities, e.g. inter- and intramuscular coordination or fatigue behavior. Based on these parameters it is possible to conclude to clinically relevant parameters such as motor control, muscular coordination or compensation strategies with different loads. In addition to this, EMG can be used in treatment itself, e.g. biofeedback-training with an EMG is an effective and evidenced based tool to improve neuromuscular control. The purpose of this workshop is to show the advantages of implementing EMG in performing artists´ health and to demonstrate additional therapy and diagnostic options.
This workshop briefly introduces the theoretical principles of EMG and the clinical applications in the context of performing artists´ health. It explains why EMG provides an additional value in the clinical reasoning process and supports the therapist, but decision making in the clinical reasoning process should never be based on EMG solely.
In the further course of the workshop the use of EMG in diagnostics and therapy (biofeedback) with performing artists is practically demonstrated and discussed with the participants.
Approach of Presentation:
1. Short presentation: introduction and understanding of EMG (educational objective 1)
2. Short case presentation of a performing artist to introduce EMG in the field of performing artists´ health and clinical reasoning (educational objective 2)
3. Interactive practical demonstration (diagnosis and biofeedback-training) as the central part of the workshop. Questions and comments will be discussed directly throughout the group (educational objective 3)
Clinical Significance:
EMG based functional neuromuscular diagnostics and biofeedback-training provides both the therapist as well as the performing artist with additional value in their clinical work.
Educational Objectives:
At the end of the workshop, the participants will be able to…
1. understand and describe the basic principles of EMG
2. understand and describe the importance of EMG in the context of performing artists´ health, physical therapy and clinical reasoning
3. use EMG on performing artists in the performance process
Unter Enclothed Cognition versteht die Wissenschaft den Einfluss der Kleidung einer Person auf ihre eigenen kognitiven Prozesse. In vergangenen Studien erzielten etwa Pro-band:innen in Arztkitteln höhere Werte bei Konzentrationstests und formell gekleidete Personen beschrieben ihren Charakter mit anderen Adjektiven als Menschen in neutraler Kleidung. Sofern solche intrapersonellen Effekte der eigenen Kleidung auf die mensch-liche Kognition konstant und in verschiedenen Kontexten auftreten sollten, sind sie von Interesse, wann immer Fähigkeiten und Persönlichkeit eines Menschen valide einge-schätzt werden sollen. Dies ist etwa in Personalauswahlverfahren der Fall, weil dort von den Ergebnissen der verwendeten Tests und Fragebögen oft wichtige Personalentschei-dungen abhängen. Um zu untersuchen, inwiefern die Kleidung eines Bewerbers oder ei-ner Bewerberin durch intrapersonelle Effekte die Ergebnisse von Auswahlverfahren be-einflusst, wurde von Mai bis November 2021 ein Laborexperiment mit studentischen 100 Proband:innen im nordwestdeutschen Osnabrück durchgeführt. Dabei wurden die Ver-suchspersonen unter Verhüllung des eigentlichen Studienzwecks entweder einer formel-len (Sakko/Blazer und Hemd/Bluse) oder einer zwanglosen Kleidungskondition (Kapu-zenpullover und Jeans) zugewiesen, in der sie zum Experiment erscheinen sollten. Dort wurden sie verschiedenen Fragebögen und Tests unterzogen. Es zeigte sich weder in der allgemeinen und situationsspezifischen Selbstwirksamkeit noch in Leistungsmotivation, Konzentration und kognitiver Leistung ein Unterschied zwischen formeller und zwang-loser Kleidung. Die vorliegende Arbeit beschreibt den theoretischen Hintergrund und die Methoden der Studie und diskutiert ihre Ergebnisse.
Der häufig vertretenen Meinung, die praktische Wirtschaftspolitik benötige keine theoretische Basis, wird mit dem vorliegenden Werk Theorie der Wirtschaftspolitik entgegnet. Ohne eine theoretische Basis, die Ziele, Instrumente, Maßnahmen und Leitsätze vorgibt, sowie die Möglichkeiten und Grenzen der Wirtschaftspolitik aufzeigt, bliebe die praktische Wirtschaftspolitik ohne Orientierung. Der Zielerfolg wäre nicht zu überprüfen. Um erfolgreich zu sein, muss die Wirtschaftspolitik Ziele anstreben und Maßnahmen treffen, die die Bürger akzeptieren. Der Erfolg der praktischen Wirtschaftspolitik ist nicht unabhängig von der Art des Wirtschaftssystems, in dem sie zum Tragen kommt.
Nostalgia is a construct that, even when rooted in lived experiences, serves the ultimate purpose of creating a desired sense of world. Fundamental cognitive competencies, including memory and imagination, are utilized by the nostalgic subject to fulfill a need for narrative coherence. A temporal or spatial distance is necessary for the occurrence of a nostalgic episode, which can be conceptualized as a “had been” state of being, as direct access to the experience is often impossible. Nostalgia may thus be viewed as a tool for sense-making rather than solely as a yearning for the past. The nostalgic narrative form is a construct that permits human subjects to comprehend their existence in the world while drawing upon their roots. These tools for sense-making serve as bridges between past experiences and current conditions. Ultimately, nostalgic identity is not just about longing for the past but also about utilizing the past as a resource for navigating the labyrinths of the present. Analyses are conducted to examine the medium of music video at three levels - auditory, visual, and linguistic - in order to investigate the strategies and techniques employed by the Iranian diaspora to create nostalgic narratives. Samples of original pieces and renditions are contrasted in order to identify elements of nostalgic narrativity. Drawing on empirical research, it is argued that the unity of a music video arises from the integration of separate layers of sensory and conceptual inputs that have been composed towards an affective resonance and narrative coherence.
Körperhaltung und Muskelspannung beeinflussen den Klang der Stimme. Aber gibt es auch einen Zusammenhang zwischen der motorischen Kontrolle der Nacken-, Gesichts- und Kieferregion und der Stimme? Die Pilotstudie mit 12 Sängerinnen ging dieser Frage nach und zeigt: Es ist sinnvoll, die motorische Kontrolle zu testen, wenn Patient*innen mit Stimmproblemen zur Physiotherapie kommen.
In modern times, closed-loop control systems (CLCSs) play a prominent role in a wide application range, from production machinery via automated vehicles to robots. CLCSs actively manipulate the actual values of a process to match predetermined setpoints, typically in real time and with remarkable precision. However, the development, modeling, tuning, and optimization of CLCSs barely exploit the potential of artificial intelligence (AI). This paper explores novel opportunities and research directions in CLCS engineering, presenting potential designs and methodologies incorporating AI. Combining these opportunities and directions makes it evident that employing AI in developing and implementing CLCSs is indeed feasible. Integrating AI into CLCS development or AI directly within CLCSs can lead to a significant improvement in stakeholder confidence. Integrating AI in CLCSs raises the question: How can AI in CLCSs be trusted so that its promising capabilities can be used safely? One does not trust AI in CLCSs due to its unknowable nature caused by its extensive set of parameters that defy complete testing. Consequently, developers working on AI-based CLCSs must be able to rate the impact of the trainable parameters on the system accurately. By following this path, this paper highlights two key aspects as essential research directions towards safe AI-based CLCSs: (I) the identification and elimination of unproductive layers in artificial neural networks (ANNs) for reducing the number of trainable parameters without influencing the overall outcome, and (II) the utilization of the solution space of an ANN to define the safety-critical scenarios of an AI-based CLCS.
Background: Multilingual children with suspected SLCN are often overlooked or their needs not accurately differentiated regarding the necessity of language support or therapy. The purpose of the study was to conceptualize, carry out and evaluate a local language support (LS) project within linguistically and culturally diverse (LCD) families and its effects on all collaborating participants.
Methods: Eight SLT students and one lecturer took part in the LS-project, alongside equivalent numbers of family liaison personnel. Students visited more than 10 young children aged between 2-6 years, and for each child 10 weekly home visits were carried out. Language enhancement was documented, several case studies with children and interviews with five liaison personnel conducted.
Results: All SLT students perceived changes in the behaviour and communication of participating children. Children in the case studies developed from pre-verbal to verbal means of communication and family liaison personnel reported positive changes alongside parental wishes to continue the support.
Conclusion: Local language support projects with LCD families can lead to positive differences regarding their children's communication development and better inclusion in mainstream society. SLT students benefit from working with LCD families and their collaborative support together with family liaison personnel, and vice versa.
Learning Outcomes: To differentiate the influence of language enhancement vs. formalized SLT therapy. To enhance the relationship with LCD clientele and collaboration with liaison personnel in SLCN settings. To incorporate life-long learning and intercultural sensitization.
Purpose
Sedentary behaviour (SED) and low level of physical activity (PA) might be associated with the development or worsening of pain. Still, studies assessing physical behaviours by accelerometry in individuals with orofacial pain are limited. This study aims to assess whether women with temporomandibular disorders (TMD) present different patterns of physical behaviours in days with (DWP) or without pain (DWoP).
Methods
Twenty-nine out of forty-four women (mean age 29.21 sd 7.96) were diagnosed with TMD and monitored over seven days using a thigh-worn accelerometer. DWP was determined when subjects presented pain in one of the craniocervical regions (head, jaw and neck) with intensity of at least 3 in the numerical rating scale. To be considered a DWoP, the individual presented less than 3 points in the three regions. Daily time-use compositions were described in terms of SED in short (<30 min) and long (≥30 min) bouts, light PA (LPA), moderate-to-vigorous PA (MVPA), and time-in-bed. Isometric log-ratios (ilr) were calculated to express the ratio of time-in-bed to time spent awake, SED relative to LPA and MVPA, SED in short relative to long bouts, and LPA relative to MVPA. Differences between DWP and DWoP were examined using MANOVA, followed by univariate post-hoc tests of pairwise differences.
Results
During DWP, women with TMD spent more time in SED in short (239 min) and long bouts (419 min), less time in LPA (245 min), MVPA (68 min), and in bed (468 min) compared with DWoP (235, 378, 263, 70 and 493 min, respectively). The MANOVA showed that all sets of ilrs did not differ statistically (ηp2 = 0.19, p = 0.25). Still, the post-hoc tests showed a trend that time spent SED relative to LPA and MVPA was larger in DWP than in DWoP (Cohen’s d = 0.36, p = 0.05).
Conclusions
Women with TMD did not show different patterns of physical behaviours in DWP or DWoP. However, there is a trend of more sedentary behaviour and less physical activity in DWP compared to DWoP. Future studies should consider other pain intensity cut-offs, isolated pain locations, and larger sample sizes to confirm these results.
The aim of this European interprofessional Health Informatics (HI) Summer School was (i) to make advanced healthcare students familiar with what HI can offer in terms of knowledge development for patient care and (ii) to give them an idea about the underlying technical and legal mechanisms. According to the students’ evaluation, interprofessional education was very well received, problem-based learning focussing on cases was rated positively and the learning goals were met. However, it was criticised that the online material provided was rather detailed and comprehensive and could have been a bit overcharging for beginners. These drawbacks were obviously compensated by the positive experience of working in international and interprofessional groups and a generally welcoming environment.
Background and Aims
Early identification of nerve lesions and associated neuropathic pain in spine-related pain disorders is important for tailored treatment. Management may consist of surgical intervention for compressive neural lesions.
With a growing waitlist for public surgical outpatient clinics in Western Australia and wait times exceeding the recommended wait time for initial assessment (Category 1 – assessment within 1 months, Category 2 within 3 months, category 3 within 12 months), a call to support new models of care has been made1, including the evaluation and expansion of workforce models supporting advanced skills in allied health.1
An Advanced Scope Physiotherapy (ASP) led Neurosurgery Spinal Clinic operates at Sir Charles Gairdner Hospital in Western Australia. The ASPs (2FTE) examine patients from the neurosurgery waitlist for their suitability for spinal surgery. Recommendation of either further investigation and possible assessment by a neurosurgeon or appropriate non-surgical management of the patients’ pain condition is suggested. Patient assessment is conducted either ‘in person’ at the hospital or via telehealth due to the remoteness of some rural patients. Patient cases are discussed with a neurosurgery consultant on a weekly basis. The aim of this project is to evaluate the ASP service in the year 2022.
Method
A retrospective descriptive analysis of patient data captured in 2022 was performed.
Results
In 2022, 1337 new patient referrals were managed plus 267 follow-ups from the previous year. Category 1 patients (n=81) waited on average 31 days for their first appointment, Category 2 patients (n=394) waited 76 days and Category 3 patients (n=854) waited 376 days.
287 (18%) referrals were discharged without physical assessment of the patient (DNA, cancellations, declined). Of the 1317 patients physically assessed by the ASPs (57%) were discharged directly after assessment, for 290 patients (22%) their outcome was still pending at time of analysis (March 2023) and 281 (22%) patients were referred for review with a neurosurgeon. Of the 229 patients assessed by a neurosurgeon (including patients from 2022), 103 patients (45%) were offered surgery, 52 (23%) were not offered surgery, 46 ( 20%) patients had to be reviewed, and for the remaining (n=18) their outcome was unknown.
Conclusion
Of the 1604 patients managed in the Neurosurgery Spinal Clinic, only 17% needed to see a neurosurgeon. The conversion rate to surgery of 45% is higher compared to an estimated 5%-10% in a non-triaged clinic.
The ASP model of care has proved invaluable to (i) provide access of patient care within the recommended wait times (ii) optimize neurosurgeons’ time, (iii) educate patients and, in case of non-suitability for surgery, advise and refer them for alternative appropriate management.
Relevance for Patient Care
The Advanced Scope Physiotherapy model of care at the Neurosurgery Spinal Clinic allows timely assessment of patients with spine-related disorders and supports targeted management of their condition.
Ethical Permissions
This project is registered as a Quality Improvement Project at Sir Charles Gairdner Hospital (QI35728) and as per the National Statement on Ethical Conduct in Human Research was exempt from review by the Sir Charles Gairdner Hospital Human Research and Ethics Committee
References
1Sustainable Health Review (2019). Sustainable Health Review: Final report to the Western Australian Government of Health, Western Australia
Workshop: “‘Sciatica’: neuropathic or not and does it matter? Outcomes from a NeuPSIG working group”
(2023)
The identification of neuropathic pain in persons with spine-related leg pain is important as this information guides treatment and management, including self-management. The NeuPSIG neuropathic pain grading system was developed to assist clinicians and researchers in determining whether patients have neuropathic pain and the level of confidence associated with that decision. Based on clinical and laboratory examination findings, patients are classified as having no neuropathic pain, possible, probable or definite neuropathic pain. Whereas this grading system works nicely in people with systemic neuropathies where sensory findings and diagnostic tests are mostly present, its application in patients with spine-related leg pain, particular in radicular pain, can be challenging. For example, in the absence of sensory changes and MRI findings, patients with radicular pain would at best reach a classification of possible neuropathic pain according to the current neuropathic pain grading system.
In this presentation I will explain the adaptations to the neuropathic pain grading system for spine-related leg pain recommended by the NeuPSIG working group. I will demonstrate its application in clinical practice using case studies and provide clarity for how the system can be incorporated in clinical trials. This will be an interactive session with audience participation.
Übergewicht wird immer mehr zu einem gesellschaftlichen Problem. Auch die Covid-19-Pandemie, die durch Homeoffice und social distancing geprägt war, verhalf nicht zur Besserung. Doch wie kann der Übergewichtigkeit entgegengewirkt werden? Diese Arbeit zeigt das Potential des Nudging- und Boosting-Ansatzes, wodurch die Menschen zu einer gesünderen Ernährung bewegt werden können. Darüber hinaus wird der Akzeptanz solcher sogenannten Nudge- und Boost-Maßnahmen nachgegangen.
Methods: Systematic review of randomized controlled trials (RCT). Searches were conducted in five electronic databases. Studies were selected if they included patients with NP over 18 years old treated with aerobic exercise (AE) (e.g., cycling, running, hiking, and walking). The main outcome of interest was pain intensity. Qualitative and quantitative data were extracted. The risk of bias (RoB) was determined using the Cochrane RoB Tool-2 and the overall certainty of the evidence with the GRADE recommendations.
Results: Out of 21,585 initial records screened, a total of six individual studies published in ten manuscripts were included. There was a great heterogeneity between protocols, comparisons, and studies’ results (different magnitudes and directions). When looking at the effect of aerobic exercise versus control groups or other interventions on pain intensity measured with the VAS, not statistically (nor clinical) significant differences between aerobic exercise and control groups (MD [95%CI] 5.16 mm [-6.38, 16.70]) were identified. The combined effect of AE plus other interventions seems to be effective. Strength exercise obtained better effects than aerobic exercises (MD [95%CI]: -11.34 mm [-21.6, -1.09]).
Conclusions: Aerobic exercise presented positive results to reduce pain intensity, and improving disability, and physical and emotional functioning. However, the evidence is restricted, low quality, and heterogeneous.
Methods: The searches were conducted on five electronic databases. RCTs or CTs with patients over 18 years old of both sexes with OFP diagnoses were targeted. The intervention of interest was AE (i.e., walking, cycling, and running), compared to any other conservative and non-conservative therapy. The primary outcome was pain intensity. Risk of bias (RoB) was done with the Cochrane RoB tool (RoB 2). The overall certainty of the evidence was evaluated with GRADE.
Results: Out of 21,585 initial records found in the initial database search, only one study (reported on three manuscripts) was included. The diagnosis of interest was headache plus temporomandibular disorders (TMD). Three treatment groups (strengthening (Str) exercise + manual therapy (MT) (G1); AE + MT + Str exercises (G2); AE (G3)) were compared. The main outcome was pain; the secondary outcomes included disability, strength, anxiety, and quality of life. The combined treatment (AE+MT+Str exercises) had the strongest effect to decrease pain and headache intensity in patients with OFP (SMD: 9.99 [95%CI: 7.19, 12.80].
Conclusions: a multimodal treatment strategy achieved the greatest positive effects on pain and other outcomes in the short/medium term. AE seems to be an important component of this strategy. However, the scientific evidence supporting AE’s isolated effect is limited, indicating a research gap in this scientific field.
The excitement sparked by the emergence of AI open platforms has encountered significant scrutiny from educators and educational planners, who have raised valid concerns about issues such as plagiarism, testing protocols, and the authenticity of content submitted by students. While these concerns are timely and crucial, it's essential not to overlook other pressing issues that often go unnoticed in the lived educational experience of learners, particularly within the field of social sciences. This paper aims to advocate for a humanistic approach with a focus on education in the generative AI Era.
Einleitung
Die Prävalenz der über 80-jährigen bei Ulcus cruris venosum (VLU) beträgt 4-5 %, obwohl diese Altersgruppe nur 1 % der Gesamtbevölkerung ausmacht. Zusätzlich wird bei VLU-Patienten häufig eine Mangelernährung beobachtet. Insbesondere geriatrische Patienten leiden darunter. Dabei ist bekannt, dass Mangelernährung Einfluss auf die Wundheilung und somit auf die Lebensqualität der Patienten hat. Diverse Studien beschreiben erste erfolgreiche ernährungstherapeutische Ansätze für einen beschleunigten Wundheilungsprozess. Allerdings ist die Ernährungstherapie bei VLU-Patienten wenig erforscht. Ziel dieser Arbeit ist es einen Überblick über den ernährungsphysiologischen Einfluss zur VLU zu schaffen, um mögliche Ernährungsinterventionen für geriatrische Patienten zu erhalten.
Hyperhydricity (HH) is one of the most important physiological disorders that negatively affects various plant tissue culture techniques. The objective of this study was to characterize optical features to allow an automated detection of HH. For this purpose, HH was induced in two plant species, apple and Arabidopsis thaliana, and the severity was quantified based on visual scoring and determination of apoplastic liquid volume. The comparison between the HH score and the apoplastic liquid volume revealed a significant correlation, but different response dynamics. Corresponding leaf reflectance spectra were collected and different approaches of spectral analyses were evaluated for their ability to identify HH-specific wavelengths. Statistical analysis of raw spectra showed significantly lower reflection of hyperhydric leaves in the VIS, NIR and SWIR region. Application of the continuum removal hull method to raw spectra identified HH-specific absorption features over time and major absorption peaks at 980 nm, 1150 nm, 1400 nm, 1520 nm, 1780 nm and 1930 nm for the various conducted experiments. Machine learning (ML) model spot checking specified the support vector machine to be most suited for classification of hyperhydric explants, with a test accuracy of 85% outperforming traditional classification via vegetation index with 63% test accuracy and the other ML models tested. Investigations on the predictor importance revealed 1950 nm, 1445 nm in SWIR region and 415 nm in the VIS region to be most important for classification. The validity of the developed spectral classifier was tested on an available hyperspectral image acquisition in the SWIR-region.
In dieser Studie wird die Umsetzbarkeit von solarthermischen Großanlagen in der südafrikanischen Getränkeindustrie mit üblicherweise großen Produktionsanlagen in den Provinzen Gauteng und Western Cape untersucht. Für die technischökonomische Bewertung werden verschiedene kommerziell verfügbare Kollektortypen gegenübergestellt, charakteristische Energiebedarfsprofile für „ready-to-drink“ Getränke definiert und Simulationen in Polysun für verschiedene Konfigurationen, mit und ohne Speicher, durchgeführt. Es zeigt sich, dass Parabolrinnenkollektoren in den wichtigsten Wirtschaftszentren Südafrikas rentabel sein können, um Gas, Schweröl, Diesel und sogar Kohle zu ersetzen, Dieser Ansatz könnte breiter auf den Lebensmittel- und Getränkesektor angewendet werden, wo die meisten Dampfheizsysteme zu finden sind.