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Institute
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Objectives: To measure and assess the economic impact of adherence to a single quality indicator (QI) regarding weaning from invasive ventilation.
Design: Retrospective observational single-centre study, based on electronic medical and administrative records.
Setting: Intensive care unit (ICU) of a German university hospital, reference centre for acute respiratory distress syndrome.
Participants: Records of 3063 consecutive mechanically ventilated patients admitted to the ICU between 2012 and 2017 were extracted, of whom 583 were eligible adults for further analysis. Patients’ weaning protocols were evaluated for daily adherence to quality standards until ICU discharge. Patients with <65% compliance were assigned to the low adherence group (LAG), patients with ≥65% to the high adherence group (HAG).
Primary and secondary outcome measures: Economic healthcare costs, clinical outcomes and patients’ characteristics.
Results: The LAG consisted of 378 patients with a median negative economic results of −€3969, HAG of 205 (−€1030), respectively (p<0.001). Median duration of ventilation was 476 (248; 769) hours in the LAG and 389 (247; 608) hours in the HAG (p<0.001). Length of stay (LOS) in the LAG on ICU was 21 (12; 35) days and 16 (11; 25) days in the HAG (p<0.001). LOS in the hospital was 36 (22; 61) days in the LAG, and within the HAG, respectively, 26 (18; 48) days (p=0.001).
Conclusions: High adherence to this single QI is associated with better clinical outcome and improved economic returns. Therefore, the results support the adherence to QI. However, the examined QI does not influence economic outcome as the decisive factor.
Hintergrund: Im Zuge der weltweiten Flüchtlingsbewegungen ist in den letzten Jahren eine hohe Anzahl an geflüchteten Personen nach Deutschland gekommen. Laut amtlicher Statistik lebten Ende 2018 ca. 1.780.000 Schutzsuchende in Deutschland (Statistisches Bundesamt 2019). Der Anteil weiblicher Schutzsuchender beträgt ca. 37,4 Prozent. Zirka 51 Prozent der geflüchteten Frauen, die in Deutschland ankommen und Asyl beantragen, befinden sich im gebärfähigen Alter zwischen 15 und 45 Jahren (Statistisches Bundesamt 2019a; _b). Darüber, wie viele schutzsuchende Frauen schwanger eingereist sind oder zum Zeitpunkt ihres Aufenthaltes in der Erstaufnahmeeinrichtung schwanger geworden sind, liegen keine Daten vor. Ebenso fehlen bisher in Deutschland repräsentative gesundheitsbezogene Daten von Schutzsuchenden (Frank, Yesil-Jürgens & Razum et al. 2017). Insbesondere zu den gesundheitlichen Problemlagen und Bedürfnissen von schutzsuchenden Frauen im Bereich Schwangerschaft, Geburt und postpartaler Phase liegen keine Erkenntnisse vor (Bozorgmehr, Mohsenpour & Saure et al. 2016; Heslehurst, Brown & Pemu et al. 2018). Internationale Studien deuten allerdings darauf hin, dass die gesundheitsbezogene Bedarfslage schutzsuchender Frauen komplex ist (Gagnon, Zimbeck & Zeitlin et al. 2009;van den Akker & van Roosmalen 2016). Die systematische Identifizierung von Versorgungsbedarfen und eine bedarfsgerechte Versorgungsplanung sind deshalb derzeit kaum möglich (Mörath 2019). Aus rechtlicher Perspektive ist diese unbefriedigende Situation ebenfalls problematisch (Klotz 2018). Die Umsetzung des völkerrechtlich bindenden internationalen Rechts auf ein für sie [Anmerk. d. V. : die Person] erreichbares Höchstmaß an körperlicher und geistiger Gesundheit (BGBI. 1976), welches von Deutschland 1976 ratifiziert wurde, sowie des UN-Übereinkommens zur Beseitigung jeder Diskriminierung der Frau von 1979 (BGBI. 1985) und der in der EU-Richtlinie 2013/33/EU in Kapitel IV aufgeführten Bestimmungen für schutzbedürftige Personen erfordert für diese spezifische Personengruppe vielfache Bemühungen. Denn die Förderung und Verbesserung der sexuellen und reproduktiven Gesundheit bzw. Rechte von schutzsuchenden Frauen kann einen Beitrag zu ihrer gesellschaftlichen Integration nach sich ziehen (Janssens, Bosmans & Temmerman 2005). Zuzüglich zur rechtlichen Situation schutzsuchender Frauen gilt das Recht ihrer Kinder auf Gesundheit. Im Artikel 24 der UN-Kinderrechtskonvention (UN, Committee on the Rights of the Child 2013) ist dieses verankert und unterstreicht u. a. für die Vor- und Nachsorge relevante Versorgungsbereiche wie z. B. prä- und postnatale Versorgung der Mütter, Aufklärung über Gesundheit und Ernährung u. w. m. (Deutsches Institut für Menschenrechte 2017).
Background
Lay family caregivers of patients receiving palliative care often confront stressful situations in the care of their loved ones. This is particularly true for families in the home-based palliative care settings, where the family caregivers are responsible for a substantial amount of the patient’s care. Yet, to our knowledge, no study to date has examined the family caregivers’ exposure to critical events and distress with home-based palliative care has been reported from Germany. Therefore, we attempt to assess family caregiver exposure to the dying patient’s critical health events and relate that to the caregiver’s own psychological distress to examine associations with general health within a home-based palliative care situation in Germany.
Methods
A cross-sectional study was conducted among 106 family caregivers with home-based palliative care in the Federal State of North Rhine Westphalia, Germany. We administered the Stressful Caregiving Adult Reactions to Experiences of Dying (SCARED) Scale. Descriptive statistics and linear regression models relating general health (SF-36) were used to analyze the data.
Results
The frequency of the caregiver’s exposure, or witness of, critical health events of the patient ranged from 95.2% “pain/discomfort” to 20.8% “family caregiver thought patient was dead”. The highest distress scores assessing fear and helpfulness were associated with “family caregiver felt patient had enough’” and “family caregiver thought patient was dead”. Linear regression analyses revealed significant inverse associations between SCARED critical health event exposure frequency (beta = .408, p = .025) and total score (beta = .377, p = .007) with general health in family caregivers.
Conclusions
Family caregivers with home-based palliative care in Germany frequently experience exposure to a large number of critical health events in caring for their family members who are terminally ill. These exposures are associated with the family caregiver’s degree of fear and helplessness and are associated with their worse general health. Thus the SCARED Scale, which is brief and easy to administer, appears able to identify these potentially upsetting critical health events among family caregivers of palliative care patients receiving care at home. Because it identified commonly encountered critical events in these patients and related them to adverse general health of family caregivers, the SCARED may add to clinically useful screens to identify family caregivers who may be struggling.
Aim: The aim of this study was to give an overview of family caregiver satisfaction within the home palliative care situation in North Rhine-Westphalia, Germany.
Design: A cross-sectional study.
Methods: An anonymous questionnaire, with seven validated scales, and comprising of 71 items, was used. The items investigated perceived needs and burdens of families within a home-based palliative care situation.
The satisfaction of the family caregivers with the services delivered by palliative care teams was measured by the FAMCARE-2 Scale. Descriptive statistics and analysis of covariance (ANCOVA) were performed.
Results: A convenience sample of 106 family members agreed to participate in the study. Overall, we found high satisfaction within our sample. There was high satisfaction with how the services respected the dignity of families, and how they provided comfort to patients. Satisfaction was lower with regard to information about patients.
Conclusion: High or low satisfaction with palliative care, tells us little about the quality of services. The high satisfaction within this study could be interpreted as a sign that palliative care was important to families at the time of availability. Regular and continuous assessment can serve to inform the continuous quality of care provision for patients and their families.
Die Hochschule Osnabrück zeichnet sich durch einen Forschungsschwerpunkt Familienorientierte geburtshilfliche Versorgung aus, welcher auf der Forschungslandkarte der Hochschulrektorenkonferenz (HRK) verzeichnet ist. Seit 2000 werden Studien zur geburtshilflichen Versorgung durchgeführt. Im Forschungsschwerpunkt IsQua wurden in vier Teilprojekten A bis D, verschiedene Instrumente zur sektorenübergreifenden Qualitätssicherung in der Lebensphase von Schwangerschaft, Geburt und Wochenbett entwickelt, erprobt und evaluiert. Mit der Entwicklung von diesen Instrumenten wird das Ziel verfolgt, Prozesse, die die physiologische Geburt befördern, zu unterstützen. Damit soll der derzeitigen Entwicklung in der Geburtshilfe gegengesteuert werden, die u. a. von hohen Interventionsraten, wie z.B. von einer anhaltend hohen Kaiserschnittrate von 32% (IQTIG [Hg.], 2017) gekennzeichnet ist.
Alle genannten Aspekte werden im Kontext eines Theorie Praxis Transfers gedacht. Instrumente wurden unter Beteiligung der Berufsgruppe der Hebammen heraus entwickelt. Sie wurden auf Anwenderebene – i. d. Regel durch Hebammen – und auf Ebene der Nutzerinnen bzw. Klientinnen, den schwangeren Frauen bzw. Müttern nach der Geburt, erprobt. Hierzu wurden vielfältige Kooperationen mit Einrichtungen des Gesundheitswesens geknüpft und verschiedene Zugänge eines Wissenstransfers hergestellt. Dieses war die Aufgabe von Teilprojekt E, welches horizontal zu den Teilprojekten A bis D angelegt war. Dabei wurde teilweise interdisziplinär mit Kollegen und Kolleginnen aus der Pflegewissenschaft und Gesundheitsökonomie gearbeitet. Inhaltlich stellt der Forschungsschwerpunkt ein nachgefragtes Thema zur Verbesserung der geburtshilflichen Versorgungsqualität regional und überregional dar.
Die dem Forschungsschwerpunkt angegliederte Graduiertenförderung im Umfang von drei Stipendien eröffnete erstmalig die Möglichkeit zur strukturierten Förderung von wissenschaftlichem Nachwuchs an Fachhochschulen in der jungen Disziplin Hebammenwissenschaft. Seit 2011 kann über eine Kooperation zwischen der Hochschule Osnabrück und der privaten Universität Witten Herdecke, Fakultät Gesundheit, die Promotion verfolgt werden. Eine weitere Dissertation konnte mit Teilprojekt A assoziiert werden. Alle Promotionen waren inhaltlich mit den einzelnen Teilprojekten verbunden.
Als Fachfrauen für Geburtshilfe verfügen Hebammen über die Kompetenz und die rechtliche Befugnis, eigenverantwortlich Geburten zu betreuen. Die Verlagerung der Geburten in die Klinik führte zu der Entwicklung, dass auch physiologische Geburten unter ärztliche Leitung gestellt wurden. Dieses wurde begleitet durch eine zunehmende Medikalisierung und Pathologisierung der physiologischen Lebensphase von Schwangerschaft, Geburt, Wochenbett und Stillzeit.
Im europäischen Ausland wurde auf diese internationale Entwicklung bereits vor 15 Jahren mit gesundheitspolitischen Maßnahmen reagiert. Im klinischen Setting sollte die physiologische Geburt durch die Einrichtung von Midwife-Led-Units eigenverantwortlich von Hebammen geleitet werden. Studien, in denen dieses Betreuungskonzept untersucht wurde, belegen, dass gesunde Frauen im Hebammenkreißsaal genauso sicher gebären wie in den üblichen ärztlich
geleiteten Kreißsälen. Darüber hinaus sind die Frauen mit der Betreuung im Hebammenkreißsaal besonders zufrieden und die Rate der operativen Eingriffe ist niedrig. Zudem eröffnet es neue Wege der interdisziplinären Zusammenarbeit im geburtshilflichen Team. Angeregt von diesen positiven Aspekten des Konzeptes Hebammenkreißsaal will der Verbund Hebammenforschung das Modell wissenschaftlich gestützt auch in Deutschland in die Praxis umsetzen und hierzulande möglichst vielen Frauen zugänglich machen. Das vorliegende Handbuch „Der Hebammenkreißsaal – Von der Idee zur Umsetzung“ richtet sich an das interessierte Fachpublikum und Hebammenkolleginnen, die die Idee eines erweiterten geburtshilflichen Versorgungskonzeptes aufgreifen und in die klinische Praxis umsetzen möchten.
Background
Forced migration significantly endangers health. Women face numerous health risks, including sexual violence, lack of contraception, sexually transmitted disease, and adverse perinatal outcomes. Therefore, sexual and reproductive healthcare is a significant aspect of women asylum seekers’ health.
Even when healthcare costs of asylum seekers are covered by the government, there may be strong barriers to healthcare access and specific needs may be addressed inadequately. The study’s objectives were a) to assess the accommodation and healthcare services provided to women asylum seekers in standard and specialised health care, b) to assess the organisation of healthcare provision and how it addresses the sexual and reproductive healthcare needs of women asylum seekers.
Methods
The study utilised a multi-method approach, comprising a less-dominant quantitative component and dominant qualitative component. The quantitative component assessed accommodation conditions for women in eight asylum centres using a survey. The qualitative component assessed healthcare provision on-site, using semi-structured interviews with health and social care professionals (n = 9). Asylum centres were selected to cover a wide range of characteristics. Interview analysis was guided by thematic analysis.
Results
The accommodation in the asylum centres provided gender-separate rooms and sanitary infrastructure. Two models of healthcare were identified, which differed in the services they provided and in their organisation: 1) a standard healthcare model characterised by a lack of coordination between healthcare providers, unavailability of essential services such as interpreters, and fragmented healthcare, and 2) a specialised healthcare model specifically tailored to the needs of asylum-seekers. Its organisation is characterised by a network of closely collaborating health professionals. It provided essential services not present in the standard model. We recommend the specialised healthcare model as a guideline for best practise.
Conclusions
The standard, non-specialised healthcare model used in some regions in Switzerland does not fully meet the healthcare needs of women asylum seekers. Specialised healthcare services used in other regions, which include translation services as well as gender and culturally sensitive care, are better suited to address these needs. More widespread use of this model would contribute significantly toward protecting the sexual and reproductive integrity and health of women asylum seekers.
In this paper, we evaluate the application of Bayesian Optimization (BO) to discrete event simulation (DES) models. In a first step, we create a simple model, for which we know the optimal set of parameter values in advance. We implement the model in SimPy, a framework for DES written in Python. We then interpret the simulation model as a black box function subject to optimization. We show that it is possible to find the optimal set of parameter values using the open source library GPyOpt. To enhance our evaluation, we create a second and more complex model. To better handle the complexity of the model, and to add a visual component, we build the second model in Simio, a commercial off-the-shelf simulation modeling tool. To apply BO to a model in Simio, we use the Simio API to write an extension for optimization plug-ins. This extension encapsulates the logic of the BO algorithm, which we deployed as a web service in the cloud.
The fact that simulation models are black box functions with regard to their behavior and the influence of their input parameters makes them an apparent candidate for Bayesian Optimization (BO). Simulation models are multivariable and stochastic, and their behavior is to a large extent unpredictable. In particular, we do not know for sure which input parameters to adjust to maximize (or minimize) the model’s outcome. In addition, the complex models can take a substantial amount of time to run.
Bayesian Optimization is a sequential and self-learning algorithm to optimize black box functions similar to as we find them in simulation models: they contain a set of parameters for which we want to identify the optimal set, they are expensive to evaluate, and they exhibit stochastic noise. BO has proven to efficiently optimize black box functions from varius disciplines. Among those, and most notably, it is successfully applied in machine learning algorithms to optimize hyperparameters.
SimBO is a flexible framework for optimizing discrete event-driven simulations (DES) using sequential optimization algorithms. While specifically designed for Bayesian Optimization (BO) in the context of DES, SimBO can be applied to any black-box problem with other optimization algorithms. The framework consists of four encapsulated components - the black-box problem, the sequential optimization algorithm, a database for experiment configuration and results, and a web-based graphical user interface - that communicate via well-defined interfaces. Each component can be run in different environments, allowing for cooperation between different hardware- and software configurations. In our research context, SimBO’s architecture enabled BO algorithms to be run on a high-performance cluster with GPU support, while the simulation is executed on a local Windows machine using the Simio simulation software. The framework’s flexibility also makes it suitable for evolving from a research-focused tool to a production-ready, cloud-based optimization tool for modern algorithms.
Background:
The evaluation of somatosensory dysfunction is important for diagnostics and may also have implications for prognosis and management. The current standard to evaluate somatosensory dysfunction is quantitative sensory testing (QST), which is expensive and time consuming. This study describes a low-cost and time-efficient clinical sensory test battery (CST), and evaluates its concurrent validity compared to QST.
Method: Three patient cohorts with carpal tunnel syndrome (CTS, n=86), non-specific neck and arm pain (NSNAP, n=40) and lumbar radicular pain/radiculopathy (LR n=26) were included. The CST consisted of 13 tests, each corresponding to a QST parameter and evaluating a broad spectrum of sensory functions using mechanical and thermal detection and pain thresholds and testing both loss and gain of function. Agreement rate, significance and strength of correlation between CST and QST were calculated.
Results: Several CST parameters (cold and warm detection, cold pain, mechanical detection, mechanical pain for loss of function, pressure pain) were significantly correlated with QST, with a majority demonstrating >60% agreement rates and weak to relatively strong correlations. However, agreement varied among cohorts. Gain of function parameters showed stronger correlation in the CTS and NSNAP cohort, whereas loss of function parameters performed better in the LR cohort. Other CST parameters (vibration detection, heat pain, mechanical pain for gain of function, windup ratio) did not significantly correlate with QST.
Conclusion: Some, but not all tests in the CST battery can detect somatosensory dysfunction as determined with QST. The CST battery may perform better when the somatosensory phenotype is more pronounced.