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Institute
Flüssigfutter bei Milchkühen
(2021)
Shredlage in der Bullenmast?
(2021)
Shredlage für Mastbullen?
(2021)
Mehr Milchleistung
(2021)
Fütterung von Zuchtstuten
(2021)
High levels of meat consumption are increasingly being criticised for ethical, environmental, and social reasons. Plant-based meat substitutes have been with reservations identified as healthy sources of protein in comparison to meat. This alternative offers several social, environmental, and probably health benefits, and it may play a role in reducing meat consumption. However, there has been a lack of research on how specific meat substitute attributes can influence consumers to replace or partially replace meat in their diets. Research has demonstrated that, in many countries, consumers are highly attached to meat. They consider it to be an essential and integral element of their daily diet. For the consumers that are not interested in vegan or vegetarian alternatives to meat, so-called meathybrids could be a low-threshold option for a more sustainable food consumption behaviour. In meathybrids, only a fraction of the meat product (e.g., 20% to 50%) is replaced with plant-based proteins. In this paper, the results of an online survey with 500 German consumers are presented with a focus on preferences and attitudes relating to meathyrids. The results show that more than fifty percent of consumers substitute meat at least occasionally. Thus, approximately half of the respondents reveal an eligible consumption behaviour with respect to sustainability and healthiness to a certain degree. Regarding the determinants of choosing either meathybrid or meat, it becomes evident that the highest effect is exerted by the health perception. The healthier meathybrids are perceived, the higher is the choice probability. Thus, this egoistic motive seems to outperform altruistic motives, like animal welfare or environmental concerns, when it comes to choice for this new product category.
Duckweed is a promising resource for future feed and food production as well as wastewater treatment. However, diseases and pests can critically limit the performance of the production systems. Patches of discolored and bleached duckweed (Lemna minor L.) appeared in hydroponic systems and spread rapidly through the crop. Pythium myriotylum was confirmed as the causing pathogen by microbiological and molecular biological analysis. This is the first report of P. myriotylum on duckweed in Germany. The result and possible countermeasures are discussed.
In order to produce protein-rich duckweed for human and animal consumption, a stable cultivation process, including an optimal nutrient supply for each species, must be implemented. Modified nutrient media, based on the N-medium for duckweed cultivation, were tested on the relative growth rate (RGR) and crude protein content (CPC) of Lemna minor and Wolffiella hyalina, as well as the decrease of nitrate-N and ammonium-N in the media. Five different nitrate-N to ammonium-N molar ratios were diluted to 10% and 50% of the original N-medium concentration. The media mainly consisted of agricultural fertilizers. A ratio of 75% nitrate-N and 25% ammonium-N, with a dilution of 50%, yielded the best results for both species. Based on the dry weight (DW), L. minor achieved a RGR of 0.23 ± 0.009 d−1 and a CPC of 37.8 ± 0.42%, while W. hyalina’s maximum RGR was 0.22 ± 0.017 d−1, with a CPC of 43.9 ± 0.34%. The relative protein yield per week and m2 was highest at this ratio and dilution, as well as the ammonium-N decrease in the corresponding medium. These results could be implemented in duckweed research and applications if a high protein content or protein yield is the aim.
Die Analyse der kommunalen Planungspraxis zur Auswahl und Bewertung von Siedlungsflächen in der Flächennutzungsplanung zeigt auf, welchen Einfluss Forschungsergebnisse auf die aktuelle Planungspraxis haben. Aufbauend auf einer Analyse des Forschungsstandes und der rechtlichen Rahmenbedingungen wird die Bewertung von Siedlungsflächen in 29 verschiedenen Flächennutzungsplänen untersucht. Als Ergebnis wurde ermittelt, dass in der Planungspraxis die Anzahl der Bewertungskriterien und die Komplexität der Bewertung in den letzten Jahren stark zugenommen hat. Außerdem kann gezeigt werden, dass und wie stark sich die Planungsmethodik und die verwendeten Kriterien zur Auswahl und Bewertung von Siedlungsflächen zwischen den einzelnen Gemeinden unterscheiden. Trotz umfangreicher anwendungsorientierter Forschung seit den 1990er Jahren zur Bewertung und Auswahl von Siedlungsflächen lassen sich jedoch nur indirekte Einflüsse der Forschungsergebnisse auf die Planungspraxis identifizieren. Teilweise wurde allerdings festgestellt, dass auch von den Gemeinden selbst neue Kriterien und Vorgehensweisen entwickelt werden.
Guided by cultural labor economics, the paper analyzes the career paths of former actors from popular television soap operas, and addresses in particular, if and under which conditions such serial engagements may function as a stepping stone for a subsequent professional acting career. A novel database of 396 German artists with detailed and long-term biographical information is used for the quantitative empirical analyses. The results indicate that soaps, contrary to popular opinion, function as a stepping stone, especially for younger actors. However, soap engagements should be rather short but long enough to allow artists to play multiple roles in other shows or films besides being in the cast of a soap. While formal acting education does not influence soap actors’ future filmographies, there is evidence that it helps artists to find jobs in arts-related occupations such as voice acting. Finally, publicity and media presence foster a later acting career. Practical implications for artists and their managers are outlined, along with a discussion on the meaning of serials for the creation and commercialization of stars.
Purpose
This paper aims to investigate the strategic consequences of manufacturing location decisions, with a focus on understanding the link between collocating manufacturing with other value chain activities, via reshoring or retaining and organizational agility.
Design/methodology/approach
The paper uses qualitative data from 115 interviews with executives from UK high value manufacturing companies to explore the recent phenomenon of reshoring and the strategic effects of manufacturing location.
Findings
The location of manufacturing is operationally and strategically important for multinational companies. The spatial dispersion of manufacturing is determined by firm-specific and external factors, both of which are subject to constant change. The analysis shows that concentrating on manufacturing in their home countries enables firms to increase organizational agility and stimulate innovation. Better integration with and more extensive collaboration between related value chain activities, such as research and development, sales and marketing, leads to higher flexibility, speed and responsiveness to customer requirements. However, under certain conditions, firms also continue to benefit from the known advantages of offshoring.
Originality/value
This research sheds light on possible strategic downsides of global value chains, characterized by dispersed activities and intermitted processes. The results provide evidence that retaining manufacturing or bringing back manufacturing operations to a company’s home country can increase organizational flexibility, speed, adaptability, innovativeness and responsiveness to customer requirements. As these capabilities are critical for long-term survival, especially in dynamic environments, firms need to review their global factory configurations and determine whether the short-term advantages of foreign locations continue to justify offshoring practices.
The ability of film stars to attract viewers is a widely accepted rationale for hiring expensive actors. However, the precise mechanisms behind this ‘drawing power’ remain unclear. By reviewing the existing literature, six possible antecedents of drawing power are identified. Artists with high acting abilities (i) increase a film’s artistic appeal, (ii) function as markers of quality and (iii) facilitate the matching process with the right audiences. Widely popular, commonly perceived as beautiful/handsome but often less talented actors, on the other hand, rather (iv) facilitate the marketing campaigns of films, (v) offer entertaining interactions with famous personalities and (vi) provide manifold opportunities for gossiping. Based on a discussion of the implications for theory and a preliminary analysis of a sample of Hollywood actors, managerial recommendations for those who have and those who depend on star drawing power are developed.
"The limits of my language are the limits of my mind. All I know is what I have words for" (Wittgenstein). When learning something completely new, we connect the unknown term to an already existing part of our knowledge. We can only build new ideas and insights upon an existing conceptual foundation. In the field of statistics, we educators frequently find ourselves met with great confusion when teaching novices. These students, entirely unfamiliar with even basic statistics, must connect the introduced statistical terms within their personal existing networks of largely non-statistical knowledge. Lecturers, on the other hand, who are well versed in statistics, have deeply internalized the content to be taught and its relevant context. The juxtaposition of the two roles may produce amusement in a lecturer upon gaining insight into the word associations made by the statistical novices. For example, a ‘logistic regression’ does not involve the ‘shipping of goods in economically difficult times,’ though this might seem entirely reasonable and intuitive to the statistics learner. Other times, these different perspectives can lead to headaches and frustration for both learners and their lecturers. In this article, we illustrate how simple statistical terms are initially connected to a student’s pre-exiting knowledge and how these associations change after completing an introductory course in applied statistics. Furthermore, we emphasize the important difference between “term”, “approach”, and “context”. Understanding this fundamental distinction may help improve the communication between the lecturer and the learner. We offer a collection of practical tools for instructors to help promote students’ conceptual understanding in a supportive, mutually-beneficial learning environment.
Die Landwirtschaft ist ein Wirtschaftszweig mit massiven Auswirkungen auf die biologische und agrobiodiverse Vielfalt. Nachhaltige Ernährung ist ein entscheidender politischer Hebel und eine realistische Chance, die Umweltauswirkungen des Agrar- und Ernährungssektors zu verringern und gleichzeitig die menschliche Gesundheit zu verbessern. Auswärts essen ist für viele Verbraucher eine immer häufiger anzutreffende Gewohnheit, und indem sie nachhaltige Gerichte anbieten, können Catering-Unternehmen eine zentrale Rolle spielen. Dazu müssen sie die Nachhaltigkeit ihres Lebensmittelangebots verstehen und richtig einschätzen können, aber es gibt noch keine gut etablierten Bewertungsinstrumente. Im Rahmen des NAHGAST-Projekts, zu dem diese Studie gehörte, wurde ein Instrument zur Bewertung der Nachhaltigkeit für Catering-Unternehmen entwickelt und getestet, das auf konkreten, pro Mahlzeit definierten Zielen basiert. Diese Studie befasst sich mit dem Mangel an Methoden zur Bewertung der Auswirkungen von Lebensmitteln auf die biologische Vielfalt, wobei der Schwerpunkt auf der Agrobiodiversität liegt. Die Arbeit veranschaulicht eine kontextspezifische Anwendung eines erweiterten DPSIR-Modells zur Strukturierung von Informationen und Auswahl von Indikatoren und schlägt eine transdisziplinäre Nutzung bestehender Messgrößen vor. Weitere Forschungsarbeiten sind erforderlich, um wissenschaftlich fundierte Zielwerte oder Nachhaltigkeitsspannen für jeden Indikator pro Mahlzeit zu definieren, damit diese berechnet werden können.
Die Stärken und Grenzen der Studie werden diskutiert.
Quantitative Umweltbewertungen sind von entscheidender Bedeutung, wenn es darum geht, effektiv auf nachhaltige Produktions- und Verbrauchsmuster hinzuarbeiten. In den letzten Jahrzehnten haben sich Lebenszyklusanalysen (LCA) als praktikables Mittel zur Messung der Umweltauswirkungen von Produkten entlang der Lieferkette etabliert. In Bezug auf Nutzer- und Konsummuster wurden jedoch methodische Schwächen festgestellt, und es wurden mehrere Versuche unternommen, Ökobilanzen entsprechend zu verbessern, beispielsweise durch Einbeziehung von Effekten höherer Ordnung und verhaltenswissenschaftlicher Unterstützung. In einer Diskussion solcher Ansätze zeigen wir, dass den Konzepten des Verbrauchs keine explizite Aufmerksamkeit geschenkt wurde, was häufig zu produktzentrierten Bewertungen führt. Wir führen Theorien sozialer Praktiken ein, um Konsummuster für LCA zugänglich zu machen. Soziale Praktiken sind routinierte Handlungen, die aus miteinander verbundenen Elementen (Materialien, Kompetenzen und Bedeutungen) bestehen, die sie als eine Einheit denkbar machen (z. B. Kochen). Da die meisten sozialen Praktiken eine Art von Verbrauch (Material, Energie, Luft) beinhalten, konnten wir einen Rahmen entwickeln, der soziale Praktiken mit der Ökobilanz verbindet. Der vorgeschlagene Rahmen bietet eine neue Perspektive für quantitative Umweltbewertungen, indem er den Schwerpunkt von Produkten oder Nutzern auf soziale Praktiken verlagert. Dementsprechend sehen wir die Chance darin, die reduktionistische Sichtweise zu überwinden, dass Menschen nur Nutzer von Produkten sind, und sie stattdessen als Praktiker in sozialen Praktiken zu sehen. Dieser Wandel könnte neue Methoden der interdisziplinären Konsumforschung ermöglichen, die beabsichtigte Sozialwissenschaften und wirkungsorientierte Bewertungen einbeziehen. Allerdings bedarf der Rahmen einer weiteren Überarbeitung und vor allem einer empirischen Validierung.
Der Konsumbereich „Ernährung“ verantwortet in Deutschland rund 15 % der Treibhausgasemissionen (THG). Aufgrund der hohen Nachfrage hat die Außer-Haus-Verpflegung eine starke Hebelwirkung, um eine klimaeffiziente Ernährung voranzutreiben – so auch Schulküchen. Aktuell sind der Verpflegung jedes Schulkindes, welches ganzjährig an der Mittagsverpflegung teilnimmt, pro Jahr etwa 264 kg THG-Emissionen zuzuschreiben.
Im Projekt KEEKS „Klima- und energieeffiziente Küche in Schulen” wurden deshalb in 22 Schulküchen von Ganztagsschulen mit täglich insgesamt 5 000 Mittagessen der Status Quo ermittelt. Dies geschah mittels Energiemessungen, Analyse von Ausstattung, Technik und Prozessen der Küchen sowie leitfadengestützten Interviews mit den Küchenleitungen. Treibhausgasemissionen von Menüs und Küchenprozessen wurden bilanziert, Einsparpotenziale identifiziert sowie Handlungsempfehlungen entwickelt und erprobt. Die effektivsten Maßnahmen – die Reduktion und Substitution von Fleisch und Fleischprodukten sowie der Aufbau eines effizienten Abfallmanagements – sparen rund 10 % des Treibhausgasausstoßes einer Schulküche ein. Die erarbeiteten Handlungsempfehlungen können Küchenpersonal dabei unterstützen, eine klimafreundliche, kindgerechte, gesunde und bezahlbare Schulküche zu gestalten.
Red pepper (Capsicum annuum L.) is one of the major spices consumed globally, recognized for its aroma and nutrient properties, and it has a major economic value for high producing countries. However, characterization of its techno-functional properties and in-depth understanding of oxidative stability is needed to produce food of high quality and stability. Thus, this work focused on the chemical, functional, thermal, oxidative stability and rheological properties of red pepper powder and paste. Experiment was designed in a Completely Randomized Design (CRD) fashion. The red pepper powder contained 14.50 g/100 g, 44.00 g/100 g and 7.57 g/100 g of crude fat, crude fiber and ash, respectively. The concentration of total phenols, carotenoids and antioxidants activity of the powder were 1.04 g GAE/100 g, 374 mg βc/100 g and 38.61 μmol TE/g, respectively. Functional properties showed lower bulk density (395.1 kg/m3) and higher tapped density (583.4 kg/m3) indicating the higher compressibility of the powder. In contrast, Hausner ratio (1.48), Carr’s index (32%) and angle of repose (45°) indicated poor flowability of the powder. Particle size distribution also indicated that the volume weighted mean values D[4,3] of the powder and paste were 262.20 and 201.46, respectively. Emulsifying capacity of the powder was 47.5%. Oil and water absorption capacities varied from 1.41 to 1.73 and 0.86 to 2.29 g/g of initial weight, respectively. Higher glass transition temperature was observed for the powder (62.54°C) than the paste (45.64°C). The induction period indicated that red pepper was more stable against oxidation in powder (5.2 h) than in the paste form (3.2 h). Rheological analysis revealed that the paste exhibited shear-thinning behavior. Overall, understanding of the properties of red pepper could contribute to enhance quality.
The increased consumption of reduced-fat or non-fat products leads to a reduced intake of fat-soluble bioactive substances, such as fat-soluble vitamins. Due to their natural role as transport systems for hydrophobic substances, casein micelles (CM) might depict a viable system. The structure of CM is characterized by a lipophilic core stabilized by an electric double layer-like structure. Modification allows accessibility of the core and, therefore, the inclusion of fat-soluble bioactive substances. Well-known modifications are pH reduction and use of rennet enzyme. A completely new procedure to modify CM structure is offered by pulsed electrical fields (PEF). The principle behind PEF is called electroporation and affects the electric double layer of CM so that it is interrupted. In this way, lipophilic substances can be incorporated into CM. In this work, we evaluated integration of β-carotene into native CM by an industry-compatible process to overcome disadvantages associated with the use of Na-caseinate and avoid great technical effort, e.g., due to treatment with high hydrostatic pressure. Our research has shown that PEF can be used for disintegration of CM and that significant amounts of β-carotene can be incorporated in CM. Furthermore, after disintegration using PEF, a combination of another PEF and thermal treatment was applied to restructure CM and trap significant amounts of β-carotene, permanently, ending up with an encapsulation efficiency of 78%.
The influence of oil content and droplet size of oil-in-water emulsions on the heat development in an ohmic heating system was investigated. The setup was run with constant power or voltage. Emulsions consisted of sunflower oil (10–50 wt%), aqua dest. (90–50 wt%) and whey protein isolate (1.25/ 2.5/ 3.75/ 5.0 and 6.25 wt%) Two different droplet size distributions were produced, large (d0.5 ≈ 2.0 μm) and small (d0.5 ≈ 0.3 μm), for each oil mass fraction. The emulsions were ohmically heated from 10 to 80 °C at a constant power of 3.0 kW and constant voltage of 15 V/cm. The electrical conductivity decreased with an increasing oil content, resulting in longer or shorter heating time for constant voltage or constant power input, respectively. The droplet size only affected the heating process at the highest oil content.
Industrial relevance
Emulsions occur in a wide range of food products (e.g. sauces, dressings, desserts) and have properties giving structure to the food system. Ohmic heating is an emerging thermal process with improved (e.g. faster or less energy required) heating characteristics. The influence of physical changes due to different droplet sizes are of interest because these might also affect the heating characteristic. In addition, the direct comparison of two different process regulations (constant power and constant voltage) indicate which set up is expedient to a successful heating process. This study aims to identify the influence of emulsion-induced structural changes and process changes on the heating rates, which is of interest for the food industry and the related machine building industry.
This study reported the impact of electron beam (e-beam) treatment on microbiota and mycotoxins naturally present in red pepper powder and physicochemical quality changes. Treatment at 6 kGy indicated significant (p < 0.05) decontamination of yeasts and molds by 3.0 and 4.4 log CFU/g, respectively. A reduction of 4.5 log CFU/g of total plate counts (TPC) was observed at 10 kGy for 23 s. Fungal inactivation followed first-order kinetics while TPC better fitted with Gompertz function (R2 = 0.9912). E-beam treatment was not efficient for the degradation of aflatoxins but indirectly controlled their production by inactivation of mycotoxigenic molds. Indeed, reduction of 25% ochratoxin A was recorded at 30 kGy retaining >85% of total phenols, carotenoids and antioxidants activity. Moreover, treatment impact on total color difference (ΔE*) indicated ‘slight differences’. Overall, e-beam treatments up to 10 kGy were efficient in decontaminating the natural microbiota without detrimental effects on the physicochemical qualities of red pepper powder.
The study aimed for the analysis of the impact of pulsed electric field (PEF) pre-treatment on convection (CD) and microwave (MW-CD) assisted air drying. Drying kinetics acceleration and retention of bioactive compounds of PEF pre-treated carrots and apples has been demonstrated. Moreover, the direct and indirect environmental energy impacts of CD and MW-CD technologies with consideration of bioactive compounds preservation has been evaluated. PEF assisted CD and MW-CD demonstrated lower energy use, especially for indirect energy consumption, in the case of carotenoids preservation in dried carrots.
Background
In mucosal barrier interfaces, flexible responses of gene expression to long-term environmental changes allow adaptation and fine-tuning for the balance of host defense and uncontrolled not-resolving inflammation. Epigenetic modifications of the chromatin confer plasticity to the genetic information and give insight into how tissues use the genetic information to adapt to environmental factors. The oral mucosa is particularly exposed to environmental stressors such as a variable microbiota. Likewise, persistent oral inflammation is the most important intrinsic risk factor for the oral inflammatory disease periodontitis and has strong potential to alter DNA-methylation patterns. The aim of the current study was to identify epigenetic changes of the oral masticatory mucosa in response to long-term inflammation that resulted in periodontitis.
Methods and results
Genome-wide CpG methylation of both inflamed and clinically uninflamed solid gingival tissue biopsies of 60 periodontitis cases was analyzed using the Infinium MethylationEPIC BeadChip. We validated and performed cell-type deconvolution for infiltrated immune cells using the EpiDish algorithm. Effect sizes of DMPs in gingival epithelial and fibroblast cells were estimated and adjusted for confounding factors using our recently developed “intercept-method”. In the current EWAS, we identified various genes that showed significantly different methylation between periodontitis-inflamed and uninflamed oral mucosa in periodontitis patients. The strongest differences were observed for genes with roles in wound healing (ROBO2, PTP4A3), cell adhesion (LPXN) and innate immune response (CCL26, DNAJC1, BPI). Enrichment analyses implied a role of epigenetic changes for vesicle trafficking gene sets.
Conclusions
Our results imply specific adaptations of the oral mucosa to a persistent inflammatory environment that involve wound repair, barrier integrity, and innate immune defense.
Background
In DNA methylation analyses like epigenome-wide association studies, effects in differentially methylated CpG sites are assessed. Two kinds of outcomes can be used for statistical analysis: Beta-values and M-values. M-values follow a normal distribution and help to detect differentially methylated CpG sites. As biological effect measures, differences of M-values are more or less meaningless. Beta-values are of more interest since they can be interpreted directly as differences in percentage of DNA methylation at a given CpG site, but they have poor statistical properties. Different frameworks are proposed for reporting estimands in DNA methylation analysis, relying on Beta-values, M-values, or both.
Results
We present and discuss four possible approaches of achieving estimands in DNA methylation analysis. In addition, we present the usage of M-values or Beta-values in the context of bioinformatical pipelines, which often demand a predefined outcome. We show the dependencies between the differences in M-values to differences in Beta-values in two data simulations: a analysis with and without confounder effect. Without present confounder effects, M-values can be used for the statistical analysis and Beta-values statistics for the reporting. If confounder effects exist, we demonstrate the deviations and correct the effects by the intercept method. Finally, we demonstrate the theoretical problem on two large human genome-wide DNA methylation datasets to verify the results.
Conclusions
The usage of M-values in the analysis of DNA methylation data will produce effect estimates, which cannot be biologically interpreted. The parallel usage of Beta-value statistics ignores possible confounder effects and can therefore not be recommended. Hence, if the differences in Beta-values are the focus of the study, the intercept method is recommendable. Hyper- or hypomethylated CpG sites must then be carefully evaluated. If an exploratory analysis of possible CpG sites is the aim of the study, M-values can be used for inference.
Background
Postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) are frequent and serious complications after surgery. We aim to investigate the association between genetic variants in cholinergic candidate genes according to the Kyoto encyclopedia of genes and genomes - pathway: cholinergic neurotransmission with the development of POD or POCD in elderly patients.
Methods
This analysis is part of the European BioCog project (www.biocog.eu), a prospective multicenter observational study with elderly surgical patients. Patients with a Mini-Mental-State-Examination score ≤ 23 points were excluded. POD was assessed up to seven days after surgery using the Nursing Delirium Screening Scale, Confusion Assessment Method and a patient chart review. POCD was assessed three months after surgery with a neuropsychological test battery. Genotyping was performed on the Illumina Infinium Global Screening Array. Associations with POD and POCD were analyzed using logistic regression analysis, adjusted for age, comorbidities and duration of anesthesia (for POCD analysis additionally for education). Odds ratios (OR) refer to minor allele counts (0, 1, 2).
Results
745 patients could be included in the POD analysis, and 452 in the POCD analysis. The rate of POD within this group was 20.8% (155 patients), and the rate of POCD was 10.2% (46 patients). In a candidate gene approach three genetic variants of the cholinergic genes CHRM2 and CHRM4 were associated with POD (OR [95% confidence interval], rs8191992: 0.61[0.46; 0.80]; rs8191992: 1.60[1.22; 2.09]; rs2067482: 1.64[1.10; 2.44]). No associations were found for POCD.
Conclusions
We found an association between genetic variants of CHRM2 and CHRM4 and POD. Further studies are needed to investigate whether disturbances in acetylcholine release and synaptic plasticity are involved in the development of POD.
A comparison study on modeling of clustered and overdispersed count data for multiple comparisons
(2021)
Data collected in various scientific fields are count data. One way to analyze such data is to compare the individual levels of the factor treatment using multiple comparisons. However, the measured individuals are often clustered – e.g. according to litter or rearing. This must be considered when estimating the parameters by a repeated measurement model. In addition, ignoring the overdispersion to which count data is prone leads to an increase of the type one error rate. We carry out simulation studies using several different data settings and compare different multiple contrast tests with parameter estimates from generalized estimation equations and generalized linear mixed models in order to observe coverage and rejection probabilities. We generate overdispersed, clustered count data in small samples as can be observed in many biological settings. We have found that the generalized estimation equations outperform generalized linear mixed models if the variance-sandwich estimator is correctly specified. Furthermore, generalized linear mixed models show problems with the convergence rate under certain data settings, but there are model implementations with lower implications exists. Finally, we use an example of genetic data to demonstrate the application of the multiple contrast test and the problems of ignoring strong overdispersion.
BACKGROUND:
Intraoperative electroencephalography (EEG) signatures related to the development of postoperative delirium (POD) in older patients are frequently studied. However, a broad analysis of the EEG dynamics including preoperative, postinduction, intraoperative and postoperative scenarios and its correlation to POD development is still lacking. We explored the relationship between perioperative EEG spectra-derived parameters and POD development, aiming to ascertain the diagnostic utility of these parameters to detect patients developing POD.
METHODS:
Patients aged ≥65 years undergoing elective surgeries that were expected to last more than 60 minutes were included in this prospective, observational single center study (Biomarker Development for Postoperative Cognitive Impairment [BioCog] study). Frontal EEGs were recorded, starting before induction of anesthesia and lasting until recovery of consciousness. EEG data were analyzed based on raw EEG files and downloaded excel data files. We performed multitaper spectral analyses of relevant EEG epochs and further used multitaper spectral estimate to calculate a corresponding spectral parameter. POD assessments were performed twice daily up to the seventh postoperative day. Our primary aim was to analyze the relation between the perioperative spectral edge frequency (SEF) and the development of POD.
RESULTS:
Of the 237 included patients, 41 (17%) patients developed POD. The preoperative EEG in POD patients was associated with lower values in both SEF (POD 13.1 ± 4.6 Hz versus no postoperative delirium [NoPOD] 17.4 ± 6.9 Hz; P = .002) and corresponding γ-band power (POD −24.33 ± 2.8 dB versus NoPOD −17.9 ± 4.81 dB), as well as reduced postinduction absolute α-band power (POD −7.37 ± 4.52 dB versus NoPOD −5 ± 5.03 dB). The ratio of SEF from the preoperative to postinduction state (SEF ratio) was ~1 in POD patients, whereas NoPOD patients showed a SEF ratio >1, thus indicating a slowing of EEG with loss of unconscious. Preoperative SEF, preoperative γ-band power, and SEF ratio were independently associated with POD (P = .025; odds ratio [OR] = 0.892, 95% confidence interval [CI], 0.808–0.986; P = .029; OR = 0.568, 95% CI, 0.342–0.944; and P = .009; OR = 0.108, 95% CI, 0.021–0.568, respectively).
CONCLUSIONS:
Lower preoperative SEF, absence of slowing in EEG while transitioning from preoperative state to unconscious state, and lower EEG power in relevant frequency bands in both these states are related to POD development. These findings may suggest an underlying pathophysiology and might be used as EEG-based marker for early identification of patients at risk to develop POD.
Objective:
The cervical mucus plugs are enriched with proteins of known immunological functions. We aimed to characterize the anti-HIV-1 activity of the cervical mucus plugs against a panel of different HIV-1 strains in the contexts of cell-free and cell-associated virus.
Design:
A cohort of consenting HIV-1-negative and HIV-1-positive pregnant women in labour was recruited from Mthatha General Hospital in the Eastern Cape province of South Africa, from whom the cervical mucus plugs were collected in 6 M guanidinium chloride with protease inhibitors and transported to our laboratories at −80 °C.
Methods:
Samples were centrifuged to remove insoluble material and dialysed before freeze--drying and subjecting them to the cell viability assays. The antiviral activities of the samples were studied using luminometric reporter assays and flow cytometry. Time-of-addition and BlaM-Vpr virus-cell fusion assays were used to pin-point the antiviral mechanisms of the cervical mucus plugs, before proteomic profiling using liquid chromatography-tandem mass spectrometry.
Results:
The proteinaceous fraction of the cervical mucus plugs exhibited anti-HIV-1 activity with inter-individual variations and some degree of specificity among different HIV-1 strains. Cell-associated HIV-1 was less susceptible to inhibition by the potent samples whenever compared with the cell-free HIV-1. The samples with high antiviral potency exhibited a distinct proteomic profile when compared with the less potent samples.
Conclusion:
The crude cervical mucus plugs exhibit anti-HIV-1 activity, which is defined by a specific proteomic profile.
Background:
Cardiac surgery patients represent a high-risk cohort in intensive care units (ICUs). Central venous pressure (CVP) measurement seems to remain an integral part in hemodynamic monitoring, especially in cardio-surgical ICUs. However, its value as a prognostic marker for organ failure is still unclear. Therefore, we analyzed postoperative CVP values after adult cardiac surgery in a large cohort with regard to its prognostic value for morbidity and mortality.
Methods:
All adult patients admitted to our ICUs between 2006 and 2019 after cardiac surgery were eligible for inclusion in the study (n = 11,198). We calculated the median initial CVP (miCVP) after admission to the ICU, which returned valid values for 9802 patients. An ROC curve analysis for optimal cut-off miCVP to predict ICU mortality was conducted with consecutive patient allocation into a (a) low miCVP (LCVP) group (≤11 mmHg) and (b) high miCVP (HCVP) group (>11 mmHg). We analyzed the impact of high miCVP on morbidity and mortality by propensity score matching (PSM) and logistic regression.
Results:
ICU mortality was increased in HCVP patients. In addition, patients in the HCVP group required longer mechanical ventilation, had a higher incidence of acute kidney injury, were more frequently treated with renal replacement therapy, and showed a higher risk for postoperative liver dysfunction, parametrized by a postoperative rise of ≥ 10 in MELD Score. Multiple regression analysis confirmed HCVP has an effect on postoperative ICU-mortality and intrahospital mortality, which seems to be independent.
Conclusions:
A high initial CVP in the early postoperative ICU course after cardiac surgery is associated with worse patient outcome. Whether or not CVP, as a readily and constantly available hemodynamic parameter, should promote clinical efforts regarding diagnostics and/or treatment, warrants further investigations.
Preoperative medication use and development of postoperative delirium and cognitive dysfunction
(2021)
Postoperative delirium (POD) and postoperative (neuro-)cognitive disorder (POCD) are frequent and serious complications after operations. We aim to investigate the association between pre-operative polypharmacy and potentially inappropriate medications and the development of POD/POCD in elderly patients. This investigation is part of the European BioCog project (www.biocog.eu), a prospective multicenter observational study with elderly surgical patients. Patients with a Mini-Mental State Examination score less than or equal to 23 points were excluded. POD was assessed up to 7 days after surgery using the Nursing Delirium Screening Scale, Confusion Assessment Method (for the intensive care unit [ICU]), and a patient chart review. POCD was assessed 3 months after surgery with a neuropsychological test battery. Pre-operative long-term medication was evaluated in terms of polypharmacy (≥5 agents) and potentially inappropriate medication (defined by the PRISCUS and European list of potentially inappropriate medications [EU(7)-PIM] lists), and associations with POD and POCD were analyzed using logistic regression analysis. Eight hundred thirty-seven participants were included for analysis of POD and 562 participants for POCD. Of these, 165 patients (19.7%) fulfilled the criteria of POD and 60 (10.7%) for POCD. After adjusting for confounders, pre-operative polypharmacy and intake of potentially inappropriate medications could not be shown to be associated with the development of POD nor POCD. We found no associations between pre-operative polypharmacy and potentially inappropriate medications and development of POD and POCD. Future studies should focus on the evaluation of drug interactions to determine whether patients benefit from a pre-operative adjustment.
Background:
Etomidate is typically used as an induction agent in cardiac surgery because it has little impact on hemodynamics. It is a known suppressor of adrenocortical function and may increase the risk for post-operative infections, sepsis, and mortality. The aim of this study was to evaluate whether etomidate increases the risk of postoperative sepsis (primary outcome) and infections (secondary outcome) compared to propofol.
Methods:
This was a retrospective before–after trial (IRB EA1/143/20) performed at a tertiary medical center in Berlin, Germany, between 10/2012 and 01/2015. Patients undergoing cardiac surgery were investigated within two observation intervals, during which etomidate and propofol were the sole induction agents.
Results:
One-thousand, four-hundred, and sixty-two patients, and 622 matched pairs, after caliper propensity-score matching, were included in the final analysis. Sepsis rates did not differ in the matched cohort (etomidate: 11.5% vs. propofol: 8.2%, p = 0.052). Patients in the etomidate interval were more likely to develop hospital-acquired pneumonia (etomidate: 18.6% vs. propofol: 14.0%, p = 0.031).
Conclusion:
Our study showed that a single-dose of etomidate is not statistically associated with higher postoperative sepsis rates after cardiac surgery, but is associated with a higher incidence of hospital-acquired pneumonia. However, there is a notable trend towards a higher sepsis rate.
The benzodiazepine, midazolam, is one of the most frequently used sedatives in intensive care medicine, but it has an unfavorable pharmacokinetic profile when continuously applied. As a consequence, patients are frequently prolonged and more deeply sedated than intended. Due to its distinct pharmacological features, including a cytochrome P450-independent metabolization, intravenous lormetazepam might be clinically advantageous compared to midazolam. In this retrospective cohort study, we compared patients who received either intravenous lormetazepam or midazolam with respect to their survival and sedation characteristics. The cohort included 3314 mechanically ventilated, critically ill patients that received one of the two drugs in a tertiary medical center in Germany between 2006 and 2018. A Cox proportional hazards model with mortality as outcome and APACHE II, age, gender, and admission mode as covariates revealed a hazard ratio of 1.75 [95% CI 1.46–2.09; p < 0.001] for in-hospital mortality associated with the use of midazolam. After additionally adjusting for sedation intensity, the HR became 1.04 [95% CI 0.83–1.31; p = 0.97]. Thus, we concluded that excessive sedation occurs more frequently in critically ill patients treated with midazolam than in patients treated with lormetazepam. These findings require further investigation in prospective trials to assess if lormetazepam, due to its ability to maintain light sedation, might be favorable over other benzodiazepines for sedation in the ICU.
Many people across the world suffer from iodine (I) deficiency and related diseases. The I content in plant-based foods is particularly low, but can be enhanced by agronomic biofortification. Therefore, in this study two field experiments were conducted under orchard conditions to assess the potential of I biofortification of apples and pears by foliar fertilization. Fruit trees were sprayed at various times during the growing season with solutions containing I in different concentrations and forms. In addition, tests were carried out to establish whether the effect of I sprays can be improved by co-application of potassium nitrate (KNO3) and sodium selenate (Na2SeO4). Iodine accumulation in apple and pear fruits was dose-dependent, with a stronger response to potassium iodide (KI) than potassium iodate (KIO3). In freshly harvested apple and pear fruits, 51% and 75% of the biofortified iodine was localized in the fruit peel, respectively. The remaining I was translocated into the fruit flesh, with a maximum of 3% reaching the core. Washing apples and pears with running deionized water reduced their I content by 14%. To achieve the targeted accumulation level of 50–100 μg I per 100 g fresh mass in washed and unpeeled fruits, foliar fertilization of 1.5 kg I per hectare and meter canopy height was required when KIO3 was applied. The addition of KNO3 and Na2SeO4 to I-containing spray solutions did not affect the I content in fruits. However, the application of KNO3 increased the total soluble solids content of the fruits by up to 1.0 °Brix compared to the control, and Na2SeO4 in the spray solution increased the fruit selenium (Se) content. Iodine sprays caused leaf necrosis, but without affecting the development and marketing quality of the fruits. Even after three months of cold storage, no adverse effects of I fertilization on general fruit characteristics were observed, however, I content of apples decreased by 20%.
Äpfel besitzen mehrere Allergene, die beim Essen innerhalb von 5–10 min zu Symptomen im Mundbereich führen – und deshalb von Apfelallergikern nicht gegessen werden können. In Deutschland haben rund 7,5 Mio. Menschen spezifische Antikörper gegen das Hauptallergen (Mal d 1) in Äpfeln entwickelt und sind damit sensibilisiert. Mindestens 3,5 Mio. von ihnen entwickeln die teilweise erheblichen allergischen Symptome als Ausdruck eines Oralen Allergie-Syndroms. Es gibt bisher keine medikamentöse Therapie gegen diese Allergie.
Apfelallergiker können daher nur auf Äpfel ganz verzichten, oder vorher erhitzte Äpfel essen oder Sorten suchen, die wenig Allergene enthalten und deshalb als allergikerfreundliche Apfelsorten bezeichnet werden können.
Alleinige Bestimmungen von Allergenen im Labor können nicht voraussagen, ob ein Apfel ohne allergische Symptome von Apfelallergikern gegessen werden kann; dazu bedarf es klinischer Prüfungen.
Wir beschreiben eine standardisierte klinische, orale Provokationstestung, die zur Charakterisierung eines allergenarmen, allergikerfreundlichen Apfels bzw. Apfelsorte benutzt werden kann.. Die Ergebnisse solcher mindestens dreijährigen Tests können zur Verleihung des ECARF-Siegels für allergikerfreundliche Produkte genutzt werden.
Background: In longitudinal studies, observations are made over time. Hence, the single observations at each time point are dependent, making them a repeated measurement. In this work, we explore a different, counterintuitive setting: At each developmental time point, a lethal observation is performed on the pregnant or nursing mother. Therefore, the single time points are independent. Furthermore, the observation in the offspring at each time point is correlated with each other because each litter consists of several (genetically linked) littermates. In addition, the observed time series is short from a statistical perspective as animal ethics prevent killing more mother mice than absolutely necessary, and murine development is short anyway. We solve these challenges by using multiple contrast tests and visualizing the change point by the use of confidence intervals.
Results: We used linear mixed models to model the variability of the mother. The estimates from the linear mixed model are then used in multiple contrast tests.There are a variety of contrasts and intuitively, we would use the Changepoint method. However, it does not deliver satisfying results. Interestingly, we found two other contrasts, both capable of answering different research questions in change point detection: i) Should a single point with change direction be found, or ii) Should the overall progression be determined? The Sequen contrast answers the first, the McDermott the second. Confidence intervals deliver effect estimates for the strength of the potential change point. Therefore, the scientist can define a biologically relevant limit of change depending on the research question.
Conclusion: We present a solution with effect estimates for short independent time series with observations nested at a given time point. Multiple contrast tests produce confidence intervals, which allow determining the position of change points or to visualize the expression course over time. We suggest to use McDermott’s method to determine if there is an overall significant change within the time frame, while Sequen is better in determining specific change points. In addition, we offer a short formula for the estimation of the maximal length of the time series.
Background
There is no consensus on the instruments for diagnosis of post-intensive care syndrome (PICS). We present a proposal for a set of outcome measurement instruments of PICS in outpatient care.
Methods
We conducted a three-round, semi-structured consensus-seeking process with medical experts, followed each by exploratory feasibility investigations with intensive care unit survivors (n1 = 5; n2 = 5; n3 = 7). Fourteen participants from nine stakeholder groups participated in the first and second consensus meeting. In the third consensus meeting, a core group of six clinical researchers refined the final outcome measurement instrument set proposal.
Results
We suggest an outcome measurement instrument set used in a two-step process. First step: Screening with brief tests covering PICS domains of (1) mental health (Patient Health Questionnaire-4 (PHQ-4)), (2) cognition (MiniCog, Animal Naming), (3) physical function (Timed Up-and-Go (TUG), handgrip strength), and (4) health-related quality of life (HRQoL) (EQ-5D-5L). Single items measure subjective health before and after the intensive care unit stay. If patients report new or worsened health problems after intensive care unit discharge and show relevant impairment in at least one of the screening tests, a second extended assessment follows: (1) Mental health (Patient Health Questionnaire-8 (PHQ-8), Generalized Anxiety Disorder Scale-7 (GAD-7), Impact of Event Scale – revised (IES-R)); (2) cognition (Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), Trail Making Test (TMT) A and B); (3) physical function (2-Minute Walk Test (2-MWT), handgrip strength, Short Physical Performance Battery (SPPB)); and (4) HRQoL (EQ-5D-5L, 12-Item WHO Disability Assessment Schedule (WHODAS 2.0)).
Conclusions
We propose an outcome measurement instrument set used in a two-step measurement of PICS, combining performance-based and patient-reported outcome measures. First-step screening is brief, free-of-charge, and easily applicable by health care professionals across different sectors. If indicated, specialized healthcare providers can perform the extended, second-step assessment. Usage of the first-step screening of our suggested outcome measurement instrument set in outpatient clinics with subsequent transfer to specialists is recommended for all intensive care unit survivors. This may increase awareness and reduce the burden of PICS.
Background
A pre-existing neurocognitive disorder (NCD) is a relevant factor for the outcome of surgical patients. To improve understanding of these conditions, we investigated the association between parameters of the cholinergic system and NCD.
Method
This investigation is part of the BioCog project (www.biocog.eu), which is a prospective multicenter observational study including patients aged 65 years and older scheduled for elective surgery. Patients with a Mini-Mental State Examination (MMSE) score ≤23 points were excluded. Neurocognitive disorder was assessed according to the fifth Diagnostic and Statistical Manual of Mental Disorders criteria. The basal forebrain cholinergic system volume (BFCSV) was assessed with magnetic resonance imaging, the peripheral cholinesterase (ChE) activities with point-of-care measurements, and anticholinergic load by analyzing the long-term medication with anticholinergic scales (Anticholinergic Drug Scale [ADS], Anticholinergic Risk Scale [ARS], Anticholinergic Cognitive Burden Scale [ACBS]). The associations of BFCSV, ChE activities, and anticholinergic scales with NCD were studied with logistic regression analysis, adjusting for confounding factors.
Results
A total of 797 participants (mean age 72 years, 42% females) were included. One hundred and eleven patients (13.9%) fulfilled criteria for mild NCD and 82 patients (10.3%) for major NCD criteria. We found that AcetylChE activity was associated with major NCD (odds ratio [95% confidence interval]: [U/gHB] 1.061 [1.010, 1.115]), as well as ADS score ([points] 1.353 [1.063, 1.723]) or ARS score, respectively ([points] 1.623 [1.100, 2.397]) with major NCD. However, we found no association between BFCSV or ButyrylChE activity with mild or major NCD.
Conclusions
AcetylChE activity and anticholinergic load were associated with major NCD. Future research should focus on the association of the cholinergic system and the development of postoperative delirium and postoperative NCD.
Acute post-operative delirium (POD) and long-term post-operative cognitive dysfunction (POCD) are frequent and associated with increased mortality, dependency on care giving and institutionalization rates. The POCD-related cost burden on the German long-term care insurance provides an indication for the savings potential from risk-adapted treatment schemes. Comprehensive estimates have not been assessed or published so far.
A model-based cost-analysis was designed to estimate POCD-related costs in the long-term care insurance. Comprehensive analysis of inpatient operations and procedures (OPS-codes) served as the base for case number calculations, which were then used as input to the actual cost model. POCD-incidence rates were obtained from the BioCog study. Various sensitivity analyses were performed to assess uncertainty of the model results.
Total POCD related annual costs in the German long-term care insurance account for approximately 1.6 billion EUR according to the base case of our analysis. Total annual costs for all POCD cases depend on surgery numbers, incidence rates, other assumptions, and uncertain input parameters.
The financial burden to the long-term care insurance is substantial, even in a conservative scenario of the cost model. Variability of results stems from uncertain assumptions, POCD-incidence rates and from uncertain patient numbers who are undergoing surgery and are therefore at risk to develop POCD.
The effect of pulsed electric field (PEF) and ultrasound (US) on the frying behavior of potato chips was investigated. For this purpose, a special fryer with a window was designed to enable the investigation of water evaporation by the characterization of bubble formation during frying. The number of water vapor bubbles and the bubble volume distribution were analyzed in order to gain an insight into heat and mass transfer affected by PEF and US treatment. Quality parameters of the potato chips such as moisture, fat and acrylamide content were measured. Overall, the results of this study show for the first time impacting effects on the frying process that can be achieved by combining PEF as a volumetric cell disintegration technology and ultrasound as a mean to affect interface phenomena. The obtained results can be used to further optimize frying processes used for the production of chips and other products.
Background and Objectives
Despite the long-standing consensus on the importance of tumor size, tumor number and carcinoembryonic antigen (CEA) levels as predictors of long-term outcomes among patients with colorectal liver metastases (CRLM), optimal prognostic cut-offs for these variables have not been established.
Methods
Patients who underwent curative-intent resection of CRLM and had available data on at least one of the three variables of interest above were selected from a multi-institutional dataset of patients with known KRAS mutational status. The resulting cohort was randomly split into training and testing datasets and recursive partitioning analysis was employed to determine optimal cut-offs. The concordance probability estimates (CPEs) for these optimal cut offs were calculated and compared to CPEs for the most widely used cut-offs in the surgical literature.
Results
A total of 1643 patients who met eligibility criteria were identified. Following recursive partitioning analysis in the training dataset, the following cut-offs were identified: 2.95 cm for tumor size, 1.5 for tumor number and 6.15 ng/ml for CEA levels. In the entire dataset, the calculated CPEs for the new tumor size (0.52), tumor number (0.56) and CEA (0.53) cut offs exceeded CPEs for other commonly employed cut-offs.
Conclusion
The current study was able to identify optimal cut-offs for the three most commonly employed prognostic factors in CRLM. While the per variable gains in discriminatory power are modest, these novel cut-offs may help produce appreciable increases in prognostic performance when combined in the context of future risk scores.
Background
Postoperative delirium (POD) is a frequent and serious complication after surgery. Evidence of a relationship between anticholinergic medication and the development of delirium is inconclusive, but studies on POD are rare.
Objectives
The objective of this study was to evaluate the anticholinergic load of preoperative medication in older adult patients and its association with the development of POD.
Methods
This investigation was part of the European BioCog project (http://www.biocog.eu), a prospective multicenter observational study in older adult surgical patients (ClinicalTrials.gov identifier: NCT02265263, 15 October 2014). Patients with a Mini–Mental State Examination score ≤ 23 points were excluded. POD was assessed up to 7 days after surgery using the Nursing Delirium Screening Scale, Confusion Assessment Method and a patient chart review. The preoperative anticholinergic load was calculated using the Anticholinergic Drug Scale (ADS), the Anticholinergic Risk Scale (ARS) and the Anticholinergic Cognitive Burden Scale (ACBS), and associations with POD were analyzed using logistic regression analysis adjusting for age, comorbidities, duration of anesthesia and number of drugs used.
Results
In total, 837 participants were included for analysis, and 165 patients (19.7%) fulfilled the criteria of POD. After adjusting for confounders, we found no association between preoperative anticholinergic load and the development of POD (ADS [points] odds ratio [OR] 0.928; 95% confidence interval [CI] 0.749–1.150; ARS [points] OR 0.832; 95% CI 0.564–1.227; ACBS [points] OR 1.045; 95% CI 0.842–1.296).
Conclusion
This study found no association between the anticholinergic load of drugs used preoperatively and the development of POD in older adult patients without severe preexisting cognitive impairment. Future analyses should examine the influence of intra- and postoperative administration of anticholinergic drugs as well as dosages of and interactions between medications.
Der vorliegende Aufsatz untersucht den Einfluss körperorientierter Influencer-Kommunikation auf die Rezipienten. Hierfür wurde im Rahmen einer Bachelorarbeit ergründet, inwiefern die Inhalte zu Verhaltensänderungen führen und wie sie sich auf die Körperwahrnehmung der Rezipienten auswirken. Die Forschung fußt auf der Theorie des sozialen Vergleichs. In einer quantitativen Inhaltsanalyse wurde kategorisiert, welche körperorientierten Influencer-Inhalte die Probandinnen sehen. Auf dieser Grundlage bauen die anschließenden Leitfadeninterviews auf. Sie wurden mithilfe einer qualitativen Inhaltsanalyse ausgewertet. Die Erkenntnisse belegen Teile der Theorie des sozialen Vergleichs. Auch stimmen sie mit aktuellen Forschungsergebnissen überein, die den Einfluss körperorientierter Influencer-Kommunikation untersuchen. Die Probandinnen erfahren überwiegend aufwärtsgerichtete, soziale Vergleiche mit den Influencer-Inhalten. Sowohl bei Inhalten, die das geltende Schönheitsideal unterstreichen, als auch bei solchen, die Selbstliebe und Akzeptanz äußerlicher Makel kommunizieren. Die Inhalte beeinflussen Verhaltensweisen der Rezipienten, besonders hinsichtlich sportlicher Aktivitäten sowie dem Umgang mit dem eigenen Körper. Der Einfluss variiert von einer positiven bis zu einer deutlich negativen Wirkung. Abhängig ist dies von Inhaltsform und zugehöriger Vergleichsrichtung: Stark aufwärtsgerichtete Vergleiche haben einen deutlich negativeren Einfluss auf die Rezipienten, als nur leicht aufwärtsgerichtete oder gleichgestellte soziale Vergleiche. Diese extremen Aufwärtsvergleiche werden besonders von Influencer-Inhalten hervorgerufen, die das geltende Schönheitsideal verkörpern. Für die Praxis bedeuten die Ergebnisse, dass körperorientierte Kommunikation deutlich bewusster und mit Blick auf das Wohlbefinden der Rezipienten geschehen muss. Auch geben sie Anlass zu weiterer Forschung: Besonders interessant wäre es, den Abwärtsvergleich zu Influencern eingehender zu untersuchen.
In der digitalisierten Arbeitswelt ermöglichen neue und flexible Informations- und Kommunikationstechnologien (IKT) eine raum- und zeitunabhängige Erreichbarkeit (Albers, 2018). Während die „ständige“ Erreichbarkeit öffentlich kontrovers diskutiert wird, zeigt sich im Bereich des Kommunikationsmanagements, insbesondere hinsichtlich der Untersuchung von Agenturen, eine Forschungslücke (Röttger & Zielmann, 2009). Dieser Beitrag knüpft daran an und liefert empirische sowie praxisnahe Erkenntnisse zur arbeitsbezogenen erweiterten Erreichbarkeit. Mit dem Fokus auf Mitarbeitende in Kommunikationsagenturen wurde untersucht, wie ihre Erreichbarkeit ausfällt und welche Gestaltungsansätze sich im Arbeitskontext daraus ableiten. Zu ihrer Beantwortung wurden qualitative, leitfadengestützte Interviews mit Vollzeitbeschäftigten (n= 10) aus mittelgroßen Agenturen (Größe: 20 bis 50 Beschäftigte, n= 5) durchgeführt und ausgewertet. Die Interviewstudie analysiert Ausmaß, Ursachen, individuelle und betriebliche Umgangsweisen sowie darauf aufbauende Handlungsansätze. Die Ergebnisse verdeutlichen zwei Aspekte der erweiterten Erreichbarkeit in Agenturen: Individualität und Vielfalt. Innerhalb der Untersuchung kann verdeutlicht werden, dass die Erreichbarkeit auf einer Kombination vielfältiger Ursachen beruht. Für die Gestaltung der Erreichbarkeit leiten sich daraus relevante Implikationen ab: Statt verbindlicher Vorschriften sollte ein selbstbestimmtes, flexibles Arbeiten im Vordergrund stehen.
Der vorliegende Aufsatz setzt sich mit dem Hostile-Media-Phänomen auseinander, nach welchem Personen, die eine starke Einstellung bei einem Thema aufweisen, die mediale Berichterstattung dazu als tendenziell konträr zu ihrer eigenen Meinung wahrnehmen (Vallone et al., 1985). Der Effekt wird durch Merkmale der Quellenangabe verstärkt, die Gruppenzugehörigkeiten des Kommunikators suggerieren (Ariyanto et al., 2007; Arpan & Raney, 2003; Gunther & Liebhart, 2006; Gunther et al., 2016; Kim & Billings, 2017; Reid, 2012). Nun wird für diese Arbeit vermutet, dass das Alter – als natürliches Merkmal – in bestimmten Kontexten als Heuristik für die ideologische Perspektive des Kommunikators fungiert. Entsprechend, so die Annahme, werden junge Befürworter bei dem Thema „Fridays for Future“ einen jungen Kommunikator mit der In-Group und einen alten Kommunikator mit der Out-Group assoziieren. Die Zuordnung des Kommunikators zu der In-Group resultiert demnach in einer Assimilation mit den Inhalten. Wird der Artikel hingegen der Out-Group zugerechnet, sollten die Inhalte abgelehnt beziehungsweise als feindlich verzerrt wahrgenommen werden. In einer experimentellen Studie wurden 108 Studierende um die Einschätzung zu einem Kommentar über „Fridays for Future“ gebeten. Der ausgewogene Text wurde entweder einem vermeintlich jungen oder alten Autor zugeschrieben. Dem Kommentar in der Version ALT wurde von den jungen Befürwortern erwartungsgemäß weniger zugestimmt als dem identischen Inhalt in der Version JUNG. Allerdings konnten keine signifikanten Unterschiede zwischen den beiden Versionen bei der Einschätzung der Ausgewogenheit des Artikels festgestellt werden. Diese Arbeit wirft einen neuen Blickwinkel auf potenziell relevante Merkmale der Quellenangabe bei der Entstehung von Hostile-Media-Effekten und gibt damit Anreize für zukünftige Forschung in diesem Bereich.
Die vorliegende Studie beschäftigt sich mit dem Einfluss der Corona-Pandemie auf die Interne Unternehmenskommunikation in Kliniken und deren interne Positionierung. Dafür wurden sechs Expert:inneninterviews mit Verantwortlichen der Internen Unternehmenskommunikation in Kliniken geführt, die anschließend durch eine qualitative Inhaltsanalyse ausgewertet wurden. Die Untersuchung zeigt, dass die Corona-Pandemie aufgrund ihrer Kriseneigenschaften eine Chance für die Bedeutung der Internen Unternehmenskommunikation in den befragten Kliniken darstellt. Dazu stellt sich heraus, dass die Krise die hierarchische Einbindung, die finanziellen Ressourcen und die interne Akzeptanz der internen Kommunikationsverantwortlichen positiv beeinflusst. Auch wenn die Pandemie nicht auf alle Aspekte der internen Positionierung einwirkt, lässt sie sich als eine Chance für die Neupositionierung der Internen Unternehmenskommunikation identifizieren. Gerade mit ihrem Einfluss auf die interne Bedeutungswahrnehmung gelingt es der Krise, an einer wichtigen Stellschraube für die Verbesserung der internen Positionierung zu drehen.
Dieser Artikel setzt sich anhand eines Beispiels mit der Frage auseinander, welchen Beitrag soziale Medien für die Pflege des kollektiven Gedächtnisses leisten und welche Risiken mit dem Einsatz von sozialen Medien in der Erinnerungskultur einhergehen. Anhand des Instagram-Projekts @ichbinsophiescholl vom SWR und BR wurden die Vor- und Nachteile von sozialen Medien unter Berücksichtigung von wissenschaftlichen Publikationen diskutiert. Zehn Monate lang, von Mai 2021 bis Februar 2022, konnten Instagram-Nutzer das Leben einer fiktiven Sophie Scholl verfolgen. Durch Storytelling und die Kombination aus fiktiven und realen Inhalten versuchten die Projektverantwortlichen, die Geschichte der Widerstandskämpferin auf dem Instagram-Kanal @ichbinsophiescholl zu erzählen. Aufgrund von fehlenden Quellenangaben und dem Verzicht darauf, fiktive Inhalte kenntlich zu machen, wurde das Projekt kritisiert. Der Vorwurf, dass das Projekt ein falsches Bild von Sophie Scholl erschafft, wurde laut. Damit trifft die Sorge, dass in sozialen Medien nicht immer zwischen anerkannter Geschichtsdarstellung, Fiktion oder Unwahrheit unterschieden werden kann, auch auf @ichbinsophiescholl zu. Es ist noch ein langer Weg, bis solche Projekte einen wertvollen Beitrag zum Erhalt der Erinnerungskultur beitragen können, ohne Gefahr zu laufen, Geschichte falsch oder unangemessen darzustellen. Um herauszufinden, wie Erinnerungsprojekte aufgebaut sein müssen, um als sinnvoller Beitrag zum kollektiven Gedächtnis wahrgenommen zu werden und eine Balance zwischen dem aktuellen Zeitgeist und einer trivialisierenden Darstellung zu finden, werden weitere wissenschaftliche Untersuchungen benötigt.
In the context of the ongoing digitization of interdisciplinary subjects, the need for digital literacy is increasing in all areas of everyday life. Furthermore, communication between science and society is facing new challenges, not least since the COVID-19 pandemic. In order to deal with these challenges and to provide target-oriented online teaching, new educational concepts for the transfer of knowledge to society are necessary. In the transfer project “Zukunftslabor Gesundheit” (ZLG), a didactic concept for the creation of E-Learning classes was developed. A key factor for the didactic concept is addressing heterogeneous target groups to reach the broadest possible spectrum of participants. The concept has already been used for the creation of the first ZLG E-Learning courses. This article outlines the central elements of the developed didactic concept and addresses the creation of the ZLG courses. The courses created so far appeal to different target groups and convey diverse types of knowledge at different levels of difficulty.
Das Unternehmen "100 Worte Sprachanalyse" hat 2021 den "HR Startup Award" erhalten, der federführend vom Bundesverband der Personalmanager (BPM) verliehen wird. Überzeugt hat 100 Worte "mit dem Versprechen, den unbewussten Gender-Bias in Stellenanzeigen zu reduzieren und unterschiedliche Grundmotive von Bewerbergruppen zu erfassen", so die Initiatoren. Doch es bestehen berechtigte Zweifel daran, dass die Software dieses Versprechen einlösen kann.
Power consumption has become a major design constraint, especially for battery-powered embedded systems. However, the impact of software applications is typically considered in later phases, where both software and hardware parts are close to their finalization. Power-related issues must be detected in early stages to keep the development costs low, satisfy time-to-market, and avoid cost-intensive redesign loops. Moreover, the variety of hardware components, architectures, and communication interfaces make the development of embedded software more challenging. To manage the complexity of software applications, approaches such as model-driven development (MDD) may be used. This article proposes a power-estimation approach in MDD for software application models in early development phases. A unified modeling language (UML) profile is introduced to model power-related properties of hardware components. To determine the impact of software applications, we defined two analysis methods using simulation data and a novel in-the-loop concept. Both methods may be applied at different development stages to determine an energy trace, describing the energy-related behavior of the system. A novel definition of energy bugs is provided to describe power-related misbehavior. We apply our approach to a sensor node example, demonstrate an energy bug detection, and compare the runtime and accuracy of the analysis methods.
Who is more eager to use Gamification in Economic Disciplines? Comparison of Students and Educators
(2022)
Background: In this paper, the focus is on the application of digital and mobile technologies as supporting tools for the implementation of gamification in the field of education of future economists. Objectives: The paper's main objective is to explore whether educators and students are motivated and willing to apply additional technologies as main gamification components in their work and education. Moreover, the paper aims to assess how their more comprehensive application affects the quality of teaching, work flexibility, new learning opportunities, and outcomes. Methods/Approach: The survey method was used to collect answers from educators and students primarily interested in accounting, finance, trade and tourism from higher and secondary education institutions in Croatia, Poland, Serbia and Germany. Afterwards, the responses were compared using statistical methods. Results: Research results confirm that educators and students are willing to use gamification in teaching. Still, they also expressed the need for better administrative support in using particular e-learning tools. Surprisingly, educators are more eager to use gamification in their work than students. Conclusions: The study's general conclusion is that educators and students are both aware of the advantages of using e-learning tools provided through digital and mobile technologies and are eager to implement more gamification in the teaching process. However, continuous education in applying new digital technologies is needed on both sides.
Background
The aim of this qualitative study was to identify a practice level model that could explain a sustained change in nutritional behavior.
Methods
The study used three data inputs from four interviewees, one merged input from a married couple, as narrative interviews. The interviews were analyzed using grounded theory.
Results
Coexistence of a certain suffering and a triggering episode lead to the decision to change nutritional life-style by all interviewed. Maintenance of the self-determined newly learned nutritional behavior was supported by subject-related intrinsic motivation, the ability to reflect, and a low expectation of success from the behavioral change. Environment-related factors were identified as support from life-partner and peers. Subjects reported that the sustained nutritional behavior change impacted their holistic health through subject-perceived improved life quality, increase in the number of social contacts, and a change in personal attitudes and perception. The analysis remains limited, and at best hypothesis generating, in that only three data inputs from four interviewees were used.
Conclusion
In this hypothesis-generating narrative interview study of four study subjects, volition, personal decision making, and long-term motivation (though not external determination) seemed to sustain a change in newly learned nutritional behavior.
Das Business Model Canvas erfreut sich in der Praxis großer Beliebtheit. Esunterstützt bei der Entwicklung von innovativen Geschäftsmodellen beiNeugründung, kann aber auch zur Evaluation bestehender Geschäftsmodelleeingesetzt werden. Durch das Business Model Canvas ist esmöglich, dieSchlüsselfaktoren eines Geschäftsmodells auf intuitive Weise strukturiert zuvisualisieren. Der vorliegende Beitrag erläutert das Business Model Canvasund nimmt eine kritische Würdigung vor.
Hintergrund
Schmerz hat einen entscheidenden Einfluss auf die humane Lebensqualität. Allein eine Wissensvergrößerung über neurobiologische Vorgänge kann das subjektive Schmerzempfinden sowie psychometrische Variablen positiv beeinflussen. Es gibt verschiedene Formen der präoperativen Patientenedukation, welche u. a. zum Ziel haben, den postoperativen Schmerz zu erklären. Laut der aktuellen Literatur liegt einer präoperativen biomedizinischen Edukation eine geringe Evidenz zugrunde. Sie kann das präoperative Angst- und Stresslevel der Patienten steigern, was sich negativ auf das postoperative Outcome auswirkt. Im Gegensatz zur biomedizinischen Edukation betrachtet das neurobiologische Verständnis den postoperativen Schmerz unter den Gesichtspunkten der Plastizität des Nervensystems und bezieht Sensibilisierungsprozesse im zentralen und peripheren Nervensystem mit ein.
Ziel
Systematische Untersuchung von Kurz- und Langzeiteffekten einer neurobiologischen (Schmerz‑)Edukation bei Patienten vor einer Wirbelsäulenoperation
Material und Methoden
Bei der Literaturrecherche wurde nach dem PI(C)O(Population Intervention Comparison Outcome)‑Schema in den medizinischen Datenbanken gesucht. 83 Artikel kamen in die engere Auswahl. Entsprechend den Ein- und Ausschlusskriterien konnten letztendlich neun Artikel eingeschlossen werden.
Ergebnisse
Durch eine präoperative neurobiologische (Schmerz‑)Edukation können postoperative Katastrophisierungstendenzen sowie die postoperative Kinesiophobie positiv beeinflusst werden. Keinen Einfluss hat eine präoperative neurobiologische Edukation auf postoperativen Schmerz und Funktion. Inkonsistenz besteht bislang in der Herangehensweise der PNE (Pain Neuroscience Education).
Schlussfolgerung
Eine präoperative Reduktion von Angst und schmerzaufrechterhaltenden Faktoren v. a. auf psychologischer und sozialer Ebene hat einen positiven Effekt auf die postoperative subjektive Schmerzbewertung, was sich in einer Reduktion von Angst, Katastrophisierungstendenzen und einer geringeren Inanspruchnahme von postoperativen Leistungen im Gesundheitswesen widerspiegelt.
A systematic study was performed to understand the effects of the devulcanizing agent dibenzamido diphenyl disulfide (DBD) on the vulcanization and devulcanization process of a sulfur-cured ethylene-propylene-diene monomer (EPDM) rubber. The influence of DBD on vulcanization was investigated by mixing DBD with virgin rubber and curative system. The devulcanization of rubber waste was achieved with varying amounts of DBD ranging from 0.4 to 13.8 wt% and temperatures from 150 to 200°C. The quality of vulcanizates and devulcanizates was evaluated by rheometer tests, temperature scanning stress relaxation measurements, and analysis of mechanical properties. During vulcanization, DBD acts as an accelerator in the presence of sulfur. When accelerators are added, the scorch time increases, and the cure rate decreases. Thus, DBD acts as a retarder. In the presence of activators, DBD leads to a significant reduction of crosslink density. This results in composites with high elongation at break and poor compression set values. The efficiency of the devulcanization of rubber waste depends strongly on DBD concentration and temperature. The monosulfidic crosslinks are cleaved by low concentrations of DBD, while polysulfidic crosslinks require higher concentrations. These results show that DBD is effective as a devulcanizing agent and degrades the network below 200°C.
One challenge of the EU energy transition is the integration of renewable electricity generation in the distribution system. EU energy law proposes a possible solution by introducing “citizen energy communities” (Directive 2019/944/EU) which may be open for “cross-border participation”. This article proposes an innovative way of implementing such cross-border communities by linking distribution systems via a “switchable element”, a generation, storage, or consumption asset with a connection to each country. An optimization model has been developed to calculate the system cost savings of such a connection. Linking regions with complementary characteristics regarding electricity generation and demand via a switchable element leads to more efficient system utilization. Findings are relevant for the transposition of “citizen energy communities” in national laws.
Der vorliegende Beitrag untersucht die Forschungsfrage, inwiefern das coronabedingte Homeoffice Führungshandeln in Kommunikationsagenturen verändert hat und inwiefern diese Veränderungen dem Führungskonzept Digital Leadership entsprechen.
Im coronabedingten Homeoffice hat die Diskussion über „Digital Leadership“ als neues Führungskonzept veränderter Arbeitswelten weiter an Relevanz gewonnen (Amerland, 2021; Bitkom, 2021; Kollmann, 2020). Dennoch zeigt sich im Bereich des Kommunikationsmanagements insbesondere hinsichtlich der Untersuchung von Agenturen eine Forschungslücke zu Digital Leadership während der Coronakrise.
Obwohl Agenturen im Berufsfeld eine große Bedeutung zugeschrieben wird, werden diese in der Forschung wenig betrachtet (Röttger und Zielmann, 2009). Daher untersucht der vorliegende Beitrag die Forschungsfrage, inwiefern das coronabedingte Homeoffice Führungshandeln in Kommunikationsagenturen verändert hat und inwiefern diese Veränderungen dem Führungskonzept Digital Leadership entsprechen. Zur Untersuchung der Forschungsfrage wurden qualitative, leitfadengestützte Experteninterviews (N = 5) mit Führungskräften aus mittelgroßen Agenturen durchgeführt und mithilfe der qualitativen Inhaltsanalyse (Mayring, 2016) ausgewertet. Die Ergebnisse zeigen entgegen der Hypothese, dass das Führungshandeln in den befragten Agenturen bereits vor der Coronakrise dem Führungskonzept „Digital Leadership“ im Sinne des VOPA+-Modells von Petry (2016) entsprach. Einzelne Merkmale des Führungskonzeptes wie Agilität und Vernetzung wurden in weiten Teilen in den befragten Agenturen durch das coronabedingte Homeoffice allerdings katalysiert. Neben einer Verlagerung der Führung in den virtuellen Raum wurden auch Veränderungen im Führungshandeln in Form neuer Maßnahmen wie mehr Fürsorge, Kommunikation und Boundary Management festgestellt. Diese Veränderungen im Führungskonzept Digital Leadership können als Implikationen für Führungskräfte in einem Modellansatz zu „Digital Leadership im Homeoffice“ festgehalten werden. Post-Covid müssen Digital Leader ihr Führungskonzept zudem an die sich weiter verändernden Anforderungen hybrider Arbeitswelten adaptieren. An dieser Stelle wird der Bedarf an weiterführender Forschung zu Führungshandeln in hybriden Arbeitswelten, insbesondere im Bereich des Kommunikationsmanagements, deutlich.
Das Ziel des Artikels besteht darin, mögliche Einsatzfelder von Nudges im Boundary-Management zu erläutern sowie die Eignung von Self-Nudging zur Stärkung der Boundary-Management-Kompetenzen von mobil arbeitenden dual Studierenden zu diskutieren. Im Rahmen einer Masterarbeit wurden zu diesem Zweck im ersten Schritt mögliche Verbindungsoptionen zwischen den beiden Forschungsfeldern aus der Theorie abgeleitet und aufgezeigt, dass diverse Nudges im Boundary-Management denkbar sind. Im zweiten Schritt wurde eine empirische Untersuchung zur Erfassung der Auswirkung von Self-Nudging auf das Boundary-Verhalten von mobil arbeitenden dual Studierenden durchgeführt. Im Zuge einer einwöchigen Feldphase wurde ein Zeitmanagement-Nudge von sechs Versuchsteilnehmenden getestet und anschließend dessen Wirksamkeit mithilfe von qualitativen Leitfadeninterviews erfasst. Die Ergebnisse der qualitativen Inhaltsanalyse zeigen, dass das Self-Nudging zur Förderung des Boundary-Management- Bewusstseins beitrug sowie die Selbstkontrolle und Selbstsorge der dual Studierenden steigerte. Der Nudge regte zur Entwicklung neuer Boundary-Taktiken und eigener Self-Nudging-Konzepte an. Dennoch resultierten keine maßgeblichen Veränderungen im Boundary-Verhalten der dual Studierenden. Zusammenfassend ist das Self-Nudging zur präventiven Förderung des Boundary-Managements beim mobilen Arbeiten geeignet, jedoch nicht zur Behebung von bereits bestehenden Boundary-Konflikten. Zudem konnte aufgezeigt werden, dass bei der Konzeption und Gestaltung von Nudges im Boundary-Management eine Ausrichtung an den Boundary-Typen nicht ausreicht, da alle Teilnehmenden verschiedene Formen des Self-Nudgings favorisierten.
Dieser Aufsatz soll auf Grundlage einer quantitativen Online-Befragung diskutieren, inwiefern digitale Nudges zur Reduzierung der Smartphone-Nutzung als wirksam eingeschätzt werden und welche Mechanismen ihre eingeschätzte Wirkung beeinflussen.
Die COVID-19-Pandemie hat das Online- Verhalten der Deutschen noch einmal deutlich in die Höhe getrieben. Mit der gestiegenen medialen Internetnutzung (um 21 Minuten pro Tag) ist auch das Smartphone zu einem immer wichtigeren Begleiter im Alltag geworden. Doch immer mehr Menschen wollen einen Rückwärtsgang einlegen und bewusst ihr digitales Konsumverhalten einschränken. Da heutzutage vermehrt Entscheidungen auf digitalen Endgeräten getroffen werden, soll dieser Aufsatz auf Grundlage einer quantitativen Online-Befragung diskutieren, inwiefern digitale Nudges zur Reduzierung der Smartphone-Nutzung als wirksam eingeschätzt werden und welche (psychologischen) Mechanismen ihre eingeschätzte Wirkung beeinflussen. Mittels eines standardisierten Fragebogens wurden sowohl verschiedene Verhaltenstendenzen, die Smartphone-Sucht und die Art des Nudges als Einflussfaktoren auf die eingeschätzte Wirksamkeit digitaler Nudges als auch der Einfluss demographischer Merkmale (Geschlecht, Alter) auf die Tendenz zur Smartphone-Sucht analysiert. Die Ergebnisse zeigen, dass die eingeschätzte Wirksamkeit digitaler Nudges von vielen individuellen Faktoren abhängt, zum Beispiel, wie stark Personen zu einem Sucht-ähnlichen Nutzungsverhalten tendieren. Für das Kommunikationsmanagement bedeutet dies, dass zu Beginn der Konzeption und Platzierung von (digitalen) Nudges eine umfassende Zielgruppenanalyse notwendig ist, um zielgerichtet Verhalten zu beeinflussen.
Der Beitrag beschäftigt sich mit der Wirksamkeit von Nudging, Boosting und Empowerment in der Gesundheitsvorsorge. Hierfür wurde die Einstellung von jungen, ernährungsbewussten
Studentinnen gegenüber vorgestellten Nudging-, Boostingund Empowerment-Maßnahmen zur gesünderen Ernährung untersucht.
Der vorliegende Aufsatz beschäftigt sich mit der Wirksamkeit von Nudging, Boosting und Empowerment in der Gesundheitsvorsorge. Hierfür wurde im Rahmen einer Bachelorarbeit eine Gruppendiskussion durchgeführt und die Einstellung von jungen, ernährungsbewussten Studentinnen gegenüber vorgestellten Nudging-, Boosting- und Empowerment-Maßnahmen zur gesünderen Ernährung untersucht. Die Diskussion wurde anhand einer qualitativen Inhaltsanalyse ausgewertet, und darauf aufbauend wurden theoretisch und empirisch fundierte Handlungsempfehlungen entwickelt. Die Ergebnisse der Untersuchung zeigen, dass keine der präsentierten Maßnahmen allein dazu motiviert, sich gesünder zu ernähren. Die Wirksamkeit hängt bei allen Konzepten maßgeblich von der Gestaltung der Maßnahmen, dem eigenen Aufwand und den mitgebrachten Voraussetzungen der Individuen ab. So greift der Nudge nicht mehr bei bereits bewussten Verbraucher*innen, und der Boost verzeichnet bei höherem eigenen Aufwand trotzdem keine deutlich höhere Wirksamkeit. Lediglich der Empowerment-Maßnahme wird eine langfristige Wirksamkeit zugeordnet, allerdings ist sie mit dem höchsten Aufwand verbunden. Auf Basis der Forschungserkenntnisse lässt sich schlussfolgern, dass ein Methoden-Mix aus kurzfristig und langfristig wirksamen kommunikativen Maßnahmen einen Weg darstellt, verschiedene Zielgruppen zu erreichen und zu gesünderer Ernährung zu motivieren.
Mitarbeiterbezogene Erwartungen und Bedürfnisse in der internen Krisenkommunikation in Unternehmen
(2022)
Ziel dieses Beitrags ist es, zum Wissen über interne Krisenkommunikation beizutragen, indem die Erwartungen und Bedürfnisse von Mitarbeitenden im Kontext der Krisenkommunikation untersucht werden. Im ersten Schritt ergab eine Literaturrecherche, dass es in von Krisen betroffenen Organisationen zu einer Fokussierung auf externe Stakeholder kommt. Interne Stakeholder werden in Krisensituationen oft vernachlässigt. Zudem gibt es einen Mangel an empirischer Evidenz über die Erwartungen und Bedürfnisse der Mitarbeitenden. Diese wurden im zweiten Schritt in einer explorativen Onlineumfrage mit 37 Mitarbeitenden verschiedener Organisationen analysiert, um empirisch fundierte Hypothesen zu generieren. Es wurden 14 Hypothesen zu den Erwartungen und Bedürfnissen der Mitarbeitenden in der internen Krisenkommunikation entwickelt. Die Ergebnisse dieser Arbeit geben Anregungen für weitere Forschungen und sind limitiert durch den Umfang der Literaturrecherche und die Teilnehmenden der durchgeführten Befragung.
Obwohl sich die Anforderungen im Sport und dem Musizieren ähneln, ist die Musikerphysiotherapie längst nicht so entwickelt wie die Sportphysiotherapie. Dabei lassen sich die sogenannten „Performance-Related Musculoskeletal Disorders“ erfolgreich mit Manueller Therapie oder Physiotherapie, z. B. mit Hilfe einer Bewegungsanalyse, therapieren. Prof. Dr. med. Christoff Zalpour gibt einen Überblick über das Feld der Musikerphysiotherapie, deren Potenzial noch lange nicht vollends erschlossen ist.
Die Anforderungen an zukünftige Teilnehmende eines Arbeitsmarktes verändern sich. Das von Frithjof Bergmann begründete Prinzip der Neuen Arbeit (Bergmann, 2004) ist aktuell Gegenstand zahlreicher Diskussionen und Debatten über aktuelle und zukünftige Arbeitswelten. Die sich daraus ergebenden Kompetenzanforderungen passen mit der Lehre in Hochschulen wenig zusammen. Zunehmend werden agile Lernszenarien diskutiert.
Das Inverted Classroom Modell (ICM) erfreut sich seit einigen Jahren großer Beliebtheit in der Hochschullehre. Aus Studierendensicht ist die Teilnahme an einer ICM-Veranstaltung aber eine Herausforderung. Für ein erfolgreiches Lernen sind insbesondere personale Kompetenzen wie Selbstmotivation, Durchhaltevermögen und Selbstregulationskompetenz erforderlich (Pöpel & Morisse, 2019). Um diesem Umstand entgegenzuwirken, wurde vom Autor ICM mit Ideen aus Scrum für eine Informatik-Lehrveranstaltung kombiniert (siehe auch (Morisse & Heidemann, 2021)). Die Wirkung von Scrum kann sich nur entfalten, wenn die Arbeit in einzelne Sprints aufgeteilt wird und bei der Bearbeitung der Sprints auch die eigene Zusammenarbeit im Rahmen einer Retrospektive kritisch reflektiert wird. Zu diesem Zweck wird der gesamte Inhalt der Lehrveranstaltung in eine Anzahl von thematischen Blöcken aufgeteilt, die als Lehr- und Lerninhalte für die Lern-Sprints der Scrum-Umsetzung werden. Für jeden Themenblock müssen die theoretischen Inhalte erarbeitet sowie eine eigenständige Zusammenfassung formuliert werden. Ergänzend dazu wurde ein Software-Produkt definiert, in dessen Rahmen die theoretischen Inhalte einfließen konnten.
Die Durchführung eines Reviews und einer Retrospektive schließen bei Scrum einen Sprint ab. Genau dies lässt sich auch im Hochschulkontext sehr gut als Feedback-Instrument durchführen. Das Review bestand in der Inspektion der entwickelten Software. Mit der Retrospektive wird die eigene Zusammenarbeit im Team kritisch reflektiert. Ein besonderes Augenmerk verdient der kommunikative Stil zwischen Lehrenden und Studierenden. Bei einem Veranstaltungskonzept, welches getragen wird von Interaktion und Diskussion, kommt einer empathischen und wertschätzenden Kommunikation eine besondere Bedeutung zu. Das dies in der vorgestellten Veranstaltung scheinbar gelungen ist, zeigt das Zitat eines der teilnehmenden Studierenden „Ich freue mich immer auf die Review-Termine“. Zur Erinnerung: Das Review ist der Termin zur Vorstellung des erreichten Ergebnisses, also eher ein Prüfungs-Setting, bei dem Studierende ihre Arbeit präsentieren. Weitere positive Resonanzmerkmale durch die Studierenden waren die hoffnungsvollen Fragen, ob denn die Veranstaltungen im kommenden Semester auch nach ICMScrum organisiert sind.
The increasing diversity of cultural backgrounds offers potential for a more elaborated information processing, yet has been shown to be challenging for individuals, due to intergroup hostility, prejudices, and difficulties of intercultural communication. Current research thus focusses on the interaction of employees with different cultural heritages, as well as on their intergroup attitudes and competences. Thereby, leaders have been shown to shape the way diversity is considered in their teams in a top-down process. However, their perception of diversity as well as related challenges and chances are poorly investigated. The current paper thus aims to contribute to the understanding of leader’s perspective on and role in diversity-management by building on a comparative qualitative study with sixteen employees and twenty-two leaders. Research questions are how employees and leaders perceive cultural diversity from their specific point of view, which experiences are likely to contribute to their opinion on and perception of diversity and in how far do employees and leaders differ in these aspects. The results show that employees are aware of the topic of diversity in general but have poor competences in dealing with diversity in their daily working life. This seems to be associated with lack of experience with intercultural interaction and a lack of support from the respective organizations/leaders. Leaders are rarely aware of this lack of support. The results indicate that leaders’ experiences with cultural and age diversity, their identification with the company and previous diversity measures in the context of the companies’ policy towards diversity seem to be relevant for the formation of leaders’ attitudes. As a consequence, most participants focus on the question whether they do or do not want diversity within their teams and companies, while they actually fail to perceive the diversity that is already there.
Oleamide is used as a lubricant in the manufacturing and application of polypropylene (PP) medical devices. Samples of PP were prepared with 0, 1500, and 15 000 ppm oleamide content as lubricant. The samples were either left non-sterile, sterilized with ethylene oxide (ETO), γ-radiation (γ) or autoclaved (A) and stored for up to 4 weeks. To determine the oleamide bulk-to-surface distribution depending on sterilization method and storage time an extraction method and a washing technique were applied. The oleamide content was determined by gas chromatography (GC-FID) and compared with the coefficient of friction (COF). The COF dependent on the measured lubricant content at the surface. The content of lubricant on the surface depends on the type of sterilization: ETO increased the lubricant content to some extent, γ-sterilization and autoclaving reduced it. After storage, no migration of the lubricant to the surface could be detected.
Farmland bird populations are in a deep crisis across Europe. Agri-environment schemes (AES) were implemented by the European Union to stop and reverse the general decline of biodiversity in agricultural landscapes. In Germany, flower strips are one of the most common AES. Establishing high-quality perennial wildflower strips (WFS) with species-rich native forb mixtures from regional seed propagation is a recent approach, for which the effectiveness for birds has not yet been sufficiently studied. We surveyed breeding birds and vegetation on 40 arable fields with WFS (20 with single and 20 with aggregated WFS) and 20 arable fields lacking WFS as controls across Saxony-Anhalt (Germany). Additionally, vegetation composition, WFS quantity and landscape structure (e.g. distance to nearest woody element) were considered in our analyses. All WFS were established with species-rich native seed mixtures (30 forbs) in agricultural practice as AES. Arable fields with WFS had a higher species richness and territory density of birds than controls, confirming the effectiveness of this AES. A forb-rich vegetation was the main driver promoting birds. Flower strip quantity at the landscape level had positive effects only on bird densities, but also single WFS achieved benefits. A short distance from WFS to woody elements increased total bird species richness. However, the density of farmland birds, which are target species of these AES, were negatively affected by the proximity and proportion of woody elements in the vicinity. The effect of the proportion of non-intensively used open habitats and overall habitat richness was unexpectedly low in the otherwise intensively farmed landscape. Species-rich perennial WFS significantly promoted breeding birds. Successful establishment of WFS, resulting in high-quality habitats, a high flower strip quantity as well as implementation in open landscapes were shown to maximise the effectiveness for restoring declining and AES target farmland birds.
Adventitious root (AR) formation is the basis of vegetative propagation in rose, be it via stem cuttings or via stenting. During this process, wounding plays a pivotal role since cell reprogramming takes place at the tissue adjacent to the wound. We investigated the effects of wounding on AR formation on leafy single-node stem cuttings of the rose rootstock R. canina ‘Pfänder’ (codes R02-3 and R02-6) and the cut rose cultivar Rosa ‘Tan09283’ (Registration name ‘Beluga’). Laser wounding treatments were based on the assisted removal of tissue layers located in the bark. The positioning of wounding was studied based on two marking directions: along the cutting base (strip pattern) and around the cutting base (ring pattern). Additionally, the effects of external supply of indole-butyric acid (IBA 1 mg L-1) on rootingwere analyzed. Results showedthat inorder toremovespecific tissue layers, the calculation of the laser energy density (J cm-2) in terms of cutting diameter was necessary. Interestingly, the application of energy densities from 2.5 J cm-2 up to approximately 8.5 J cm-2 were sufficient to expose the tissue layers of epidermis up to regions of phloem. Regarding AR formation for R. canina ‘Pfänder’, characterized by a low rooting response, an increase in the rooting percentage was registered when the laser treatment eliminated the tissue up to phloem proximities. Analysis of the nodal position showed that bud location was a preferential place for AR formation independently of wounding treatment. In case of Rosa ‘Tan09283’, laser treatments did not reduce its high rooting capacity, but an apparent reduction in rooting quality due to an investment in tissue healing was observed when wounding reached deeper layers such as parenchyma and sclerenchyma. Results also showeda strongARformation directly fromwounded regions in case of Rosa ‘Tan09283’ specifically when the woundwas located below the axillary bud. In conclusion, wounding by assisted-elimination of layers by laser can induce positive effects on AR formation of single-node stemcuttings of the rose if energy applied is able to expose phloemproximities,a longitudinalorientation, and relative position to the axillary bud are considered.
In open-field vegetable production, high quantities of soil mineral nitrogen (Nmin) and N-rich crop residues often remain in the field at harvest. After the harvest of crops in autumn, this N can lead to considerable nitrate (NO3−) losses during the subsequent winter leaching period. In four field trials, different tillage depths (3–4, 10, 30 cm) and dates (early autumn, late autumn, early spring) were investigated to reduce N losses after growing spinach in the autumn. In a further treatment, the nitrification inhibitor 3,4-Dimethylpyrazole phosphate (DMPP) was directly applied to the crop residues. Potential N losses were calculated by a balance sheet approach based on Nmin concentration (0–90 cm), measured N mineralization and N uptake by catch crops. By postponing the tillage date from early to late autumn or spring, resprouting spinach stubbles acted as a catch crop, reducing N losses by up to 61 kg ha−1. However, if the spinach biomass collapsed, the N losses increased by up to 33 kg ha−1 even without tillage. The application of DMPP as well as the tillage depth were less effective. Overall, postponing tillage to spring seems to be the most promising approach for reducing N losses during the off-season.
Hintergrund: Die Digitalisierung durchdringt mittlerweile alle Bereiche unseres Lebens und zunehmend auch das Handlungsfeld der Pflege. Mithilfe medial gestützter Lehrgestaltung können Lernende auf digitale Herausforderungen ihres Berufsalltags vorbereitet werden. Zudem müssen Pflegende über ein individuell und fallbezogen anwendbares Fachwissen verfügen, welches mittels des Konzeptes der hermeneutischen Fallarbeit vermittelt wird. Virtuelle Simulationen können authentische Fallszenarien darstellen und das konventionelle Konzept der Fallarbeit mit moderner Technik erweitern.
Ziel: Ziel der Recherche ist, national und international verwendete Arten digitaler und virtueller Medien in Verbindung mit der Methode der hermeneutischen Fallarbeit im Kontext der Gesundheitsbildung zu identifizieren und dessen Nutzen zu beschreiben.
Methoden: Es ist eine Literaturrecherche im Design eines systematischen Reviews in den Datenbanken CINAHL, MEDLINE via PubMed, Cochrane und Springer Link durchgeführt und mit dem Schneeballprinzip ergänzt worden.
Ergebnisse: Es wurden elf Publikationen eingeschlossen. Die Ergebnisse zeigen überwiegend positive Auswirkungen, die sich in elf Kategorien unterteilen lassen. Schlussfolgerung: Der Einsatz von virtuellen Patient_innen wird auch in der empirischen und mediendidaktischen
Forschung als ein effektives und effizientes Lernarrangement angesehen. Sowohl im positiven wie auch negativen Sinne, sind die Ergebnisse abhängig von der didaktisch-methodischen Aufarbeitung, dem Design der Lernmodule und der Qualität des Mediums wie auch der Lehre.
Freshwater ecosystems host disproportionately high numbers of species relative to their surface area yet are poorly protected globally. We used data on the distribution of 1631 species of aquatic plant, mollusc, odonate and fish in 18,816 river and lake catchments in Europe to establish spatial conservation priorities based on the occurrence of threatened, rangerestricted and endemic species using the Marxan systematic conservation planning tool. We found that priorities were highest for rivers and ancient lakes in S Europe, large rivers and lakes in E and N Europe, smaller lakes in NW Europe and karst/limestone areas in the Balkans, S France and central Europe. The a priori inclusion of well-protected catchments resulted in geographically more balanced priorities and better coverage of threatened (critically endangered, endangered and vulnerable) species. The a priori exclusion of well-protected catchments showed that priority areas that need further conservation interventions are in S and E Europe. We developed three ways to evaluate the correspondence between conservation priority and current protection by assessing whether a cathment has more (or less) priority given its protection level relative to all other catchments. Each method found that priority relative to protection was high in S and E Europe and generally low in NW Europe. The inclusion of hydrological connectivity had little influence on these patterns but decreased the coverage of threatened species, indicating a trade-off between connectivity and conservation of threatened species. Our results suggest that catchments in S and E Europe need urgent conservation attention (protected areas, restoration, management, species protection) in the face of imminent threats such as river regulation, dam construction, hydropower development and climate change. Our study presents continental-scale conservation priorities for freshwater ecosystems in ecologically meaningful planning units and will thus be important in freshwater biodiversity conservation policy and practice, and water management in Europe.
The energy transition can be mapped on four levels. While industry and the state should act on the national and international level, most of the energy transition is taking place at the regional and municipal levels. Here the small-scale and decentralized nature of the new energy world is reflected, where customized individual solutions are created.
Information systems (IS) play a central role in promoting corporate sustainability and pro-environmental behavior. This study explores the use of mobile apps for fostering sustainability-oriented corporate culture. It accentuates issues relating to sustainability-oriented corporate culture (RQ1), app meta-requirements as a strategic approach to addressing these issues (RQ2), as well as design and implementation principles (RQ3). Referring to the literature on sustainability apps, gamification, and nudging, our qualitative research design combines an analysis of four corporate apps intending to promote sustainable behavior and expert interviews (Grounded Theory). The proposed framework supports the planning, realization, and monitoring of this targeted app use. Single cultural dimensions inform seven issues in culture development. Five meta-requirements address this multi-dimensionality, challenges provided by new digital working environments, and principles of Green IT. Four design principles support, extend, and integrate current knowledge on app features, nudging, and gamification. Five variables determine the app intervention and maturity level. We conclude that this targeted app use should intend to foster the sustainability orientation within all dimensions of corporate culture instead of being limited to promoting sustainable behavior.
Der vorliegende Beitrag fokussiert die Bedeutung Nachhaltigkeitsorientierter Unternehmenskultur für den Einsatz von künstlicher Intelligenz im Marketing. Spezifischer skizzieren wir die Einflussmöglichkeiten auf den Einsatz nachhaltiger künstlicher Intelligenz zur Förderung des Sustainable Development Goals 12 (Nachhaltige/r Produktion & Konsum). In einem diskursiven Ansatz führt dieser Beitrag Erkenntnisse aus der Literatur zur nachhaltigkeitsorientierten Unternehmenskultur, nachhaltigen künstlicher Intelligenz und dem Nachhaltigkeitsmarketing zusammen und bildet diese mithilfe des St. Galler Managementmodells ab.