Refine
Document Type
- Article (9)
- Conference Proceeding (7)
Is part of the Bibliography
- yes (16)
Keywords
- Vitamin D (3)
- 25-hydroxycholecalciferol (2)
- Bone metabolism (2)
- 25-Hydroxycholecalciferol (1)
- 25‐hydroxycholecalciferol (1)
- Bone development (1)
- Ferkel (1)
- Locomotion (1)
- Mineral supply (1)
- Pig nutrition (1)
Institute
- Fakultät AuL (16) (remove)
The present study aims to compare the effects of maternal and offspring treatment with 25-hydroxycholecalciferol (25-OHD3) and vitamin D3 on vitamin D status, mineral homoeostasis, bone metabolism and locomotion in the offspring. Either vitamin D3 (50 μg/kg diet) or 25-OHD3 (50 μg/kg diet) was supplemented to the gestation and lactation diets of 49 multiparous sows and/or to the diets of their growing offspring. Treatment of the sows did not affect plasma concentrations of 25-OHD3 of the offspring. Pigs fed 25-OHD3 had higher plasma concentrations of 25-OHD3 than pigs that received vitamin D3 during rearing and fattening. However, neither plasma concentrations of calcium, phosphate and bone markers during the observation period nor bone ash and bone mineral density at slaughter were clearly affected by the treatment. Maternal and offspring treatment with 25-OHD3 instead of vitamin D3 resulted in a slight reduction in the prevalence of leg swelling. In addition, more pigs walked with even steps and normal stride length. Further studies are needed to test whether the slight effects observed in the present experiment are reproducible and of relevance for animal health and welfare. In that case, the underlying mechanisms should be revealed in order to take advantage of potentially beneficial influences especially under certain feeding regimes.
Lahmheiten bilden bei Sauen und wachsenden Schweinen ein ernstzunehmendes Gesundheits- und Tierwohlproblem. Die Studie zeigte, dass der diätetische Einsatz von 25-Hydroxycholecalciferol im Austausch zum Vitamin D3 zu einer Reduktion von Bewegungsproblemen bei Sauen und wachsenden Schweinen geführt hat.
Vitamin D für starke Beine
(2023)
Wirkung eines Vitamin D3-Metaboliten (25-OH-D3) auf den Geburtsverlauf von hochleistenden Sauen
(2022)
25-hydroxycholecalciferol (25-OHD3) formed via hepatic hydroxylation from vitamin D, cholecalciferol, represents the precursor of the biologically active vitamin D hormone, 1,25-dihydroxyvitamin D. Due to a higher absorption rate and the omission of one hydroxylation, dietary supplementation of 25-OHD3 instead of vitamin D3 is considered to be more efficient as plasma concentrations of 25-OHD3 are increased more pronounced. The present review summarises studies investigating potential beneficial effects on mineral homeostasis, bone metabolism, health status and performance in sows, piglets and fattening pigs. Results are inconsistent. While most studies could not demonstrate any or only a slight impact of partial or total replacement of vitamin D3 by 25-OHD3, some experiments indicated that 25-OHD3 might alter physiological processes when animals are challenged, for example, by a restricted mineral supply.