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Characterisation of pain in people with hereditary neuropathy with liability to pressure palsy
(2017)
Hereditary neuropathy with liability to pressure palsy (HNPP) has historically been considered a pain-free condition, though some people with HNPP also complain of pain. This study characterised persistent pain in people with HNPP. Participants provided cross-sectional demographic data, information on the presence of neurological and persistent pain symptoms, and the degree to which these interfered with daily life. The painDETECT and Central Sensitization Inventory questionnaires were used to indicate potential neuropathic, central sensitisation and musculoskeletal (nociceptive) pain mechanisms. Additionally, participants were asked if they thought that pain was related to/part of HNPP. 32/43 (74%) subjects with HNPP had persistent pain and experience this pain in the last week. Of those with pain, 24 (75%) were likely to have neuropathic pain and 27 (84%) were likely to have central sensitisation. All 32 participants felt that their pain could be related to/part of their HNPP. Significant negative impact of the pain was common. Pain characterisation identified neuropathic pain and/or central sensitisation as common, potential underlying processes. Pain may plausibly be directly related to the underlying pathophysiology of HNPP. Further consideration of including pain as a primary symptom of HNPP is warranted.
Model Driven Architecture (MDA): Integration and Model Reuse for Open Source eLearning Platforms
(2005)
Every modern institution involved in higher education needs a Learning Management System (LMS) to handle learning and teaching processes. It is necessary to offer e.g. electronic lecture materials to the students for download via the internet. In some educational contexts, it is also necessary to offer internet tutorials to be able to give the students more personal support and accompany them through the whole lecture period. Many organisations have introduced commercial LMS and gained the experience that monolithic solutions do not fulfil the dynamic requirements of complex educational institutions and are very cost-intensive. Therefore, many universities face the decision to stick to their commercial LMS or to switch to a potentially more cost-effective and flexible solution, for instance by adopting available Open Source LMS. Since we have made profound experience in developing and operating an Open Source LMS, this contribution enlightens the main characteristics of this alternative. This paper describes a use case dealing with a full product lifecycle (development, deployment, use and evaluation) of an Open Source LMS at the University of Muenster (Germany). It identifies relevant instruments and aspects of system design which software architects in practical application domains should pay attention to.
Data warehouse systems have become a basic technological infrastructure in management decision making. Nevertheless, the overall utility of data warehouses remains unmeasured in most practical cases. As a consequence of this, IT-managers do not possess appropriate means to evaluate warehouse benefits in order to decide about investments in warehousing technology. This paper develops a controlling instrument for data warehouse systems based on the Balanced Scorecard (BSC) approach. On the basis of the technological aspects of data warehouse systems, the BSC perspectives are developed and populated with relevant objectives and measures for datawarehouse success. These perspectives are integrated into a consistent data warehouse scorecard. Finally, this instrument provides a holistic approach to drive the performance of data warehouse systems.
Positive factors are increasingly recognized in the field of psychology, however, few studies have investigated the longitudinal measurement invariance (LMI) and reciprocal associations of positive core constructs, such as happiness, life satisfaction and positive mental health. This study evaluated the LMI of these constructs over four years in a Chinese Student Sample (n = 4400) using the Subjective Happiness Scale (SHS), the Satisfaction with Life Scale (SWLS) and the Positive Mental Health Scale (PMH-scale). The longitudinal reciprocal associations of the constructs were examined within a random intercept cross-lagged panel model (RI-CLPM). The results show that the SHS, SWLS and PMH-scale are measurement invariant over time and that the constructs are positively inter-related, but show different reciprocal patterns over time.