Refine
Year of publication
- 2022 (89) (remove)
Document Type
- Article (40)
- Conference Proceeding (38)
- Book (4)
- Part of a Book (3)
- Other (2)
- Bachelor Thesis (1)
- Preprint (1)
Language
- English (89) (remove)
Keywords
- Landscape Planning (3)
- performing artists (3)
- physiotherapy (3)
- Amino acid (2)
- Climate Resilience (2)
- Electroporation (2)
- Entrepreneurship (2)
- Green Fingers (2)
- Landscape Design (2)
- Lemnaceae (2)
Institute
- Fakultät AuL (46)
- Fakultät WiSo (27)
- Fakultät IuI (9)
- Institut für Management und Technik (4)
- Institut für Duale Studiengänge (3)
Taking the transdisciplinary research study “Green fingers for a climate resilient city”, funded by the German Ministry of education and research (BMBF), as an example, this paper follows the hypothesis that processes of landscape planning and designing multifunctional green spaces and processes of co-creation need to be combined to stimulate climate resilient city transformation. The findings are that efforts to combine these processes benefit from making complex climate-resilient city planning accessible for people of different professional backgrounds. The paper showcases how storytelling (Schmidt 2019), mapping (Langner 2009) and guided walks (Schultz 2019) are means to mutually engage with, perceive and understand multifunctional green spaces, inspire ownership, and build capacity for the city’s climate-resilient transformation.
Background
A peripheral venous catheter (PVC) is the most widely used device for obtaining vascular access, allowing the administration of fluids and medication. Up to 25% of adult patients, and 50% of pediatric patients experience a first-attempt cannulation failure. In addition to patient and clinician characteristics, device features might affect the handling and success rates. The objective of the study was to compare the first-attempt cannulation success rate between PVCs with wings and a port access (Vasofix® Safety, B. Braun, abbreviated hereon in as VS) with those without (Introcan® Safety, B. Braun, abbreviated hereon in as IS) in an anesthesiological cohort.
Methods
An open label, multi-center, randomized trial was performed. First-attempt cannulation success rates were examined, along with relevant patient, clinician, and device characteristics with univariate and multivariate analyses. Information on handling and adherence to use instructions was gathered, and available catheters were assessed for damage.
Results
Two thousand three hundred four patients were included in the intention to treat analysis. First-attempt success rate was significantly higher with winged and ported catheters (VS) than with the non-winged, non-ported design (IS) (87.5% with VS vs. 78.2% with IS; PChi < .001). Operators rated the handling of VS as superior (rating of “good” or “very good: 86.1% VS vs. 20.8% IS, PChi < .001). Reinsertion of the needle into the catheter after partial withdrawal—prior or during the catheterization attempt—was associated with an increased risk of cannulation failure (7.909, CI 5.989–10.443, P < .001 and 23.023, CI 10.372–51.105, P < .001, respectively) and a twofold risk of catheter damage (OR 1.999, CI 1.347–2.967, P = .001).
Conclusions
First-attempt cannulation success of peripheral, ported, winged catheters was higher compared to non-ported, non-winged devices. The handling of the winged and ported design was better rated by the clinicians. Needle reinsertions are related to an increase in rates of catheter damage and cannulation failure.
During gestation, the most drastic change in oxygen supply occurs with the onset of ventilation after birth. As the too early exposure of premature infants to high arterial oxygen pressure leads to characteristic diseases, we studied the adaptation of the oxygen sensing system and its targets, the hypoxia-inducible factor- (HIF-) regulated genes (HRGs) in the developing lung. We draw a detailed picture of the oxygen sensing system by integrating information from qPCR, immunoblotting, in situ hybridization, and single-cell RNA sequencing data in ex vivo and in vivo models. HIF1α protein was completely destabilized with the onset of pulmonary ventilation, but did not coincide with expression changes in bona fide HRGs. We observed a modified composition of the HIF-PHD system from intrauterine to neonatal phases: Phd3 was significantly decreased, while Hif2a showed a strong increase and the Hif3a isoform Ipas exclusively peaked at P0. Colocalization studies point to the Hif1a-Phd1 axis as the main regulator of the HIF-PHD system in mouse lung development, complemented by the Hif3a-Phd3 axis during gestation. Hif3a isoform expression showed a stepwise adaptation during the periods of saccular and alveolar differentiation. With a strong hypoxic stimulus, lung ex vivo organ cultures displayed a functioning HIF system at every developmental stage. Approaches with systemic hypoxia or roxadustat treatment revealed only a limited in vivo response of HRGs. Understanding the interplay of the oxygen sensing system components during the transition from saccular to alveolar phases of lung development might help to counteract prematurity-associated diseases like bronchopulmonary dysplasia.
Venous leg ulcers and diabetic foot ulcers are the most common chronic wounds. Their prevalence has been increasing significantly over the last years, consuming scarce care resources. This study aimed to explore the performance of detection and classification algorithms for these types of wounds in images. To this end, algorithms of the YoloV5 family of pre-trained models were applied to 885 images containing at least one of the two wound types. The YoloV5m6 model provided the highest precision (0.942) and a high recall value (0.837). Its mAP_0.5:0.95 was 0.642. While the latter value is comparable to the ones reported in the literature, precision and recall were considerably higher. In conclusion, our results on good wound detection and classification may reveal a path towards (semi-) automated entry of wound information in patient records. To strengthen the trust of clinicians, we are currently incorporating a dashboard where clinicians can check the validity of the predictions against their expertise.
Knowledge of the small-scale nutrient status of a field is an important basis for decision-making when it comes to optimising the fertiliser use in crop production. Currently, the traditional method involves soil sampling in the field and soil sample analysis in the laboratory as two separate working processes.
The previous research project "soil2data" developed a mobile field laboratory for different carrier vehicles. In the follow-up project "prototypes4soil2data", the results of soil2data are further developed. A mixed soil sample is collected during the drive on the field. The soil sample is then wet-chemically prepared and analysed. The overall soil sampling and analysis process is divided into the following process steps: soil sampling planning, soil sampling, soil preparation, soil analysis and data management. The process steps are modified for the mobile field laboratory and the process steps run in parallel. The new soil extraction method is based on official German methods (VDLUFA) to ensure the interoperability of the analysis results with the VDLUFA fertiliser recommendations. An innovative key component is the NUTRISTAT analysis module (lab-on-chip with ISFET measurement technology). It can measure pH, the nutrients NO3-, H2PO4-, K+ and the electrical conductivity. In addition to the advantages of rapid data availability and no need to transport soil material to the laboratory, it provides a future basis for new application, e.g. verification of current results in the field during soil sampling with existing results or dynamic adjustment of soil sampling during work in the field.
Applications of pulsed electric fields for processing potatoes: Examples and equipment design
(2022)
In the last two decades, pulsed electric fields (PEF) have successfully been introduced into the food industry, as one of the most promising and "game changing" technologies. This review is devoted to the recent applications of pulsed electric fields used in processing potatoes. The potato processing market size was estimated to be ca. USD 24.83 billion (2018) and with an annual growth rate of 5.2%. The physicochemical characteristics of potatoes and the specificity of potato processing lines makes a pulsed electric field very versatile and flexible allowing one to achieve different technological aims by its implementation into technological lines. In this paper, a short analysis of the potato structure and its nutritional properties, applications of moderate electric fields, ohmic heating, and pulsed electric fields are presented. Moreover, the basic electroporation effects, metabolic responses, texture modification and different PEF assisted processes applied to the potato are discussed. Finally, some examples of commercial applications and a brief description of the available equipment for the PEF processing of potatoes are presented.
Diabetic foot ulcer (DFU) is a chronic wound and a common diabetic complication as 2% – 6% of diabetic patients witness the onset thereof. The DFU can lead to severe health threats such as infection and lower leg amputations, Coordination of interdisciplinary wound care requires well-written but time-consuming wound documentation. Artificial intelligence (AI) systems lend themselves to be tested to extract information from wound images, e.g. maceration, to fill the wound documentation. A convolutional neural network was therefore trained on 326 augmented DFU images to distinguish macerated from unmacerated wounds. The system was validated on 108 unaugmented images. The classification system achieved a recall of 0.69 and a precision of 0.67. The overall accuracy was 0.69. The results show that AI systems can classify DFU images for macerations and that those systems could support clinicians with data entry. However, the validation statistics should be further improved for use in real clinical settings. In summary, this paper can contribute to the development of methods to automatic wound documentation.
There are a number of well-established concepts explaining decision-making. The sociology of wise practice within public administration suggests that thinking preferences like the use of intuition form a cornerstone of public administrators’ virtuous practice. This contribution uses conceptual and theoretical resources from the behavioral sciences and public administration to account for individual level differences of employees with regard to thinking preferences in the public sector. Institutional frameworks and social structures may enable or impede the habituation of virtue. The contribution empirically investigates this proposition with respondents from North America and the European Union. The analysis investigates the behavioral dimension preference for intuition/preference for deliberation. An analysis of data from 333 employees from organizations in North America and 1644 employees from organizations in the EU reveal prevalent differences in the preference for thinking styles. The public and private sector differ significantly in terms of the preference for rational as well as for intuitive thinking. What is exciting is that private employees rank higher than public employees on both scales, whereas the difference in rational thinking shows a small effect and the effect size in regard of intuitive thinking is negligible. We explore possible explanations for such differences and similarities.