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SimBO is a flexible framework for optimizing discrete event-driven simulations (DES) using sequential optimization algorithms. While specifically designed for Bayesian Optimization (BO) in the context of DES, SimBO can be applied to any black-box problem with other optimization algorithms. The framework consists of four encapsulated components - the black-box problem, the sequential optimization algorithm, a database for experiment configuration and results, and a web-based graphical user interface - that communicate via well-defined interfaces. Each component can be run in different environments, allowing for cooperation between different hardware- and software configurations. In our research context, SimBO’s architecture enabled BO algorithms to be run on a high-performance cluster with GPU support, while the simulation is executed on a local Windows machine using the Simio simulation software. The framework’s flexibility also makes it suitable for evolving from a research-focused tool to a production-ready, cloud-based optimization tool for modern algorithms.
Unter Enclothed Cognition versteht die Wissenschaft den Einfluss der Kleidung einer Person auf ihre eigenen kognitiven Prozesse. In vergangenen Studien erzielten etwa Pro-band:innen in Arztkitteln höhere Werte bei Konzentrationstests und formell gekleidete Personen beschrieben ihren Charakter mit anderen Adjektiven als Menschen in neutraler Kleidung. Sofern solche intrapersonellen Effekte der eigenen Kleidung auf die mensch-liche Kognition konstant und in verschiedenen Kontexten auftreten sollten, sind sie von Interesse, wann immer Fähigkeiten und Persönlichkeit eines Menschen valide einge-schätzt werden sollen. Dies ist etwa in Personalauswahlverfahren der Fall, weil dort von den Ergebnissen der verwendeten Tests und Fragebögen oft wichtige Personalentschei-dungen abhängen. Um zu untersuchen, inwiefern die Kleidung eines Bewerbers oder ei-ner Bewerberin durch intrapersonelle Effekte die Ergebnisse von Auswahlverfahren be-einflusst, wurde von Mai bis November 2021 ein Laborexperiment mit studentischen 100 Proband:innen im nordwestdeutschen Osnabrück durchgeführt. Dabei wurden die Ver-suchspersonen unter Verhüllung des eigentlichen Studienzwecks entweder einer formel-len (Sakko/Blazer und Hemd/Bluse) oder einer zwanglosen Kleidungskondition (Kapu-zenpullover und Jeans) zugewiesen, in der sie zum Experiment erscheinen sollten. Dort wurden sie verschiedenen Fragebögen und Tests unterzogen. Es zeigte sich weder in der allgemeinen und situationsspezifischen Selbstwirksamkeit noch in Leistungsmotivation, Konzentration und kognitiver Leistung ein Unterschied zwischen formeller und zwang-loser Kleidung. Die vorliegende Arbeit beschreibt den theoretischen Hintergrund und die Methoden der Studie und diskutiert ihre Ergebnisse.
Introduction Postoperative delirium (POD) is seen in approximately 15% of elderly patients and is related to poorer outcomes. In 2017, the Federal Joint Committee (Gemeinsamer Bundesausschuss) introduced a ‘quality contract’ (QC) as a new instrument to improve healthcare in Germany. One of the four areas for improvement of in-patient care is the ‘Prevention of POD in the care of elderly patients’ (QC-POD), as a means to reduce the risk of developing POD and its complications.
The Institute for Quality Assurance and Transparency in Health Care identified gaps in the in-patient care of elderly patients related to the prevention, screening and treatment of POD, as required by consensus-based and evidence-based delirium guidelines. This paper introduces the QC-POD protocol, which aims to implement these guidelines into the clinical routine. There is an urgent need for well-structured, standardised and interdisciplinary pathways that enable the reliable screening and treatment of POD. Along with effective preventive measures, these concepts have a considerable potential to improve the care of elderly patients.
Methods and analysis The QC-POD study is a non-randomised, pre–post, monocentric, prospective trial with an interventional concept following a baseline control period. The QC-POD trial was initiated on 1 April 2020 between Charité-Universitätsmedizin Berlin and the German health insurance company BARMER and will end on 30 June 2023. Inclusion criteria: patients 70 years of age or older that are scheduled for a surgical procedure requiring anaesthesia and insurance with the QC partner (BARMER). Exclusion criteria included patients with a language barrier, moribund patients and those unwilling or unable to provide informed consent. The QC-POD protocol provides perioperative intervention at least two times per day, with delirium screening and non-pharmacological preventive measures.
Ethics and dissemination This protocol was approved by the ethics committee of the Charité-Universitätsmedizin, Berlin, Germany (EA1/054/20). The results will be published in a peer-reviewed scientific journal and presented at national and international conferences.
A brief questionnaire for measuring alarm fatigue in nurses and physicians in intensive care units
(2023)
When exposed to hundreds of medical device alarms per day, intensive care unit (ICU) staff can develop “alarm fatigue” (i.e., desensitisation to alarms). However, no standardised way of quantifying alarm fatigue exists. We aimed to develop a brief questionnaire for measuring alarm fatigue in nurses and physicians. After developing a list of initial items based on a literature review, we conducted 15 cognitive interviews with the target group (13 nurses and two physicians) to ensure that the items are face valid and comprehensible. We then asked 32 experts on alarm fatigue to judge whether the items are suited for measuring alarm fatigue. The resulting 27 items were sent to nurses and physicians from 15 ICUs of a large German hospital. We used exploratory factor analysis to further reduce the number of items and to identify scales. A total of 585 submissions from 707 participants could be analysed (of which 14% were physicians and 64% were nurses). The simple structure of a two-factor model was achieved within three rounds. The final questionnaire (called Charité Alarm Fatigue Questionnaire; CAFQa) consists of nine items along two scales (i.e., the “alarm stress scale” and the “alarm coping scale”). The CAFQa is a brief questionnaire that allows clinical alarm researchers to quantify the alarm fatigue of nurses and physicians. It should not take more than five minutes to administer.
Der häufig vertretenen Meinung, die praktische Wirtschaftspolitik benötige keine theoretische Basis, wird mit dem vorliegenden Werk Theorie der Wirtschaftspolitik entgegnet. Ohne eine theoretische Basis, die Ziele, Instrumente, Maßnahmen und Leitsätze vorgibt, sowie die Möglichkeiten und Grenzen der Wirtschaftspolitik aufzeigt, bliebe die praktische Wirtschaftspolitik ohne Orientierung. Der Zielerfolg wäre nicht zu überprüfen. Um erfolgreich zu sein, muss die Wirtschaftspolitik Ziele anstreben und Maßnahmen treffen, die die Bürger akzeptieren. Der Erfolg der praktischen Wirtschaftspolitik ist nicht unabhängig von der Art des Wirtschaftssystems, in dem sie zum Tragen kommt.
This paper investigates four different mobile robots with respect to their drivingcharacteristics and soil preservation properties in an agricultural environment.Thereby, robots of classical design from agriculture as well as systems from spacerobotics with advanced locomotion concepts are considered to determine theindividual advantages of each rover concept with respect to the application domain.Locomotion experiments were conducted to analyze the general driving behavior,tensile force, and obstacle‐surmounting capability and ground interaction of eachrobot. Various soil conditions typical for the area of application are taken intoaccount, which are varied in terms of moisture and density. The presented workcovers the specification of the conducted experiments, documentation of theimplementation as well as analysis and evaluation of the collected data. In theevaluation, particular attention is paid to the change in driving characteristics underdifferent soil conditions, as well as to the soil stress caused by driving, since soilquality is of critical importance for agricultural applications. The analysis shows thatthe advanced locomotion concepts, as used in space robotics, also have positiveimplications for certain requirements in agricultural applications, such as maneuver-ability in wet conditions and soil conservation. The results show potential for designinnovations in agricultural robotics that can be used, to open up new fields ofapplication for instance in the context of precision farming.