Refine
Year of publication
Document Type
- Article (1488) (remove)
Language
- German (1110)
- English (367)
- Portuguese (7)
- French (1)
- Multiple languages (1)
- Dutch (1)
- Russian (1)
Keywords
- Nachhaltigkeit (8)
- Logistik (6)
- Danube (4)
- Electroporation (4)
- Evaluation (4)
- Lemnaceae (4)
- Neurodynamik (4)
- Nutritional footprint (4)
- Physiotherapie (4)
- Sustainability (4)
Institute
Vergleich der Effekte eines funktionellen Stabilisations- mit einem Standardtraining auf Schmerz, Funktion, Kinematik der unteren Extremität und des Rumpfes, Ausdauerfähigkeit der Rumpfmuskulatur und der Kraft der exzentrischen Kniegelenks- und Hüftmuskultur bei Frauen mit patellofemoralen Schmerzen.
Biomechanische Analysen sind in der Lage, menschliche Bewegungen valide und umfassend zu erfassen und auszuwerten. Neben den beiden großen Bereichen Kinetik und Kinematik bietet die Elektromyografie (EMG) eine zuverlässige Möglichkeit, die neuromuskuläre Aktivität zu analysieren. Mithilfe des EMG können neuromuskuläre Parameter erhoben werden, die präzise Aussagen beispielsweise zur inter- und intramuskulären Koordination, der Muskelfaserverteilung, des Ermüdungsverhaltens oder des Timings zulassen.
Für verlässliche Daten sind im klinischen Setting jedoch einige wichtige Faktoren zu berücksichtigen. Diese sind von großer Bedeutung und sollten vor einer Analyse beachtet werden. Daneben hängt ein effektiver Einsatz des EMG im klinischen Setting von der Integration in den Clinical-Reasoning-Prozess ab. Die jeweilige individuelle Patientensituation benötigt eine klare Fragestellung. Dazu kann auf ein Ebenenmodell aufgebaut werden, welches die biomechanischen Steuerungsgrößen in der klinischen Anwendung berücksichtigt.
Der Artikel stellt die physiologischen Grundlagen der Elektromyografie, die Einflüsse von Verletzungen auf die Muskelfaserzusammensetzung, die grundlegende Signalverarbeitung und Dateninterpretation, ein Ebenenmodell für die klinische Anwendung sowie Einsatzfelder in der Physiotherapie vor.
Das Forschungsprojekt „Dorfgemeinschaft 2.0“ hat zum Ziel, dem Bedürfnis der Bürger_innen nachzukommen, auch im Alter zu Hause wohnen bleiben zu können. Die Gesundheitsversorgung im ländlichen Raum steht im Mittelpunkt. Hierfür werden regional angepasste Lösungsstrategien anhand des Design Science Ansatzes entworfen und individuelle Wünsche und Bedarfe multiperspektivisch in den Blick genommen. Vier der so entstandenen Versorgungskonzepte werden als nutzerorientierte alltags und gesundheitsbezogene Ansätze vorgestellt. Zudem werden die angedachten Kommunikationsstrukturen und das Zusammenwirken der Konzepte als Versorgungsnetz auf dem virtuellen Dorfmarktplatz beschrieben.
Ziel des Beitrags ist die Identifikation von Problemen, Meta-Anforderungen und Designprinzipien für den Einsatz von Mixed und Virtual Reality Brillen zur Unterstützung nicht-ärztlichen Fachpersonals bei zahnmedizinischen Hausbesuchen. Im Rahmen von zwei Gruppendiskussionen und einem Experteninterview wurden zunächst mögliche Einsatzszenarien identifiziert. Anschließend wurde eine systematische Literaturrecherche in den Datenbanken CINAHL, Business Source Premier und MEDLINE durchgeführt. In der gefundenen Literatur konnten 14 Probleme bei der Anwendung von Mixed und Virtual Reality Brillen identifiziert werden. Darauf basierend wurden 14 Meta-Anforderungen abgeleitet und in fünf Designprinzipien zusammengefasst. Abschließend wurden die Ergebnisse mit den Spezifikationen der Microsoft HoloLens 2 abgeglichen, um eine Eignung für die Unterstützung der geplanten Hausbesuche festzustellen. Zudem wurde ein Umsetzungskonzept skizziert. Die Ergebnisse dienen als wichtige Empfehlungen für die praxisnahe Umsetzung zukünftiger Konzepte bezüglich der Anwendung von Mixed und Virtual Reality Brillen im (zahn-)medizinischen Kontext. Die Literaturrecherche zeigt eine Forschungslücke im Bereich zahnmedizinischer Hausbesuche auf. Die Ergebnisse dieses Beitrags schaffen daher eine solide Basis für die zukünftige Forschung.
Flexibility in planning through frequent amendments. The practice of land use planning in Germany
(2022)
How can formal planning deal with uncertainty and rapid change while maintaining high standards of procedural certainty? This paper, using Germany as an example, examines how municipalities handle this dilemma within their existing planning systems. Municipalities use different approaches, ranging from regular redrafting to comprehensive changes or regular amendments. Amendments and complementary informal plans are important components of flexibility in planning. We argue that the choice to make frequent amendments instead of redrafting the preparatory land-use plan does not necessarily lead to a loss of a city-wide, long-term perspective, provided amendments are prepared and justified using informal concepts.
Bericht über das 35. Symposium der Performing Arts Medicine Association in Snowmass, Colorado
(2018)
Objectives: Among varied challenges of COVID-19, challenges in food and nutrition security world-over are critical. We compared the nutritional policy responses in India and Germany since both countries differ on the Human Development Index, yet both have committed to the G20 common policy response to COVID-19, besides the comparability of two large and heterogeneously populated countries, both having democratic governments.
Methods: Policy research publications were reviewed using qualitative meta-policy approach. We used comparative case-study. Recent food and nutrition policies of G20 nations of India and Germany were evaluated.
Results: India has primarily targeted her public distribution system and Germany has primarily targeted her food markets in order to manage the food and nutrition security in response to COVID-19. Both countries are coordinating additional associated nutritional policies, policies and strategies to effect an integrated sectoral approach to COVID-19 management. Both are using corrective measures of the process management strategies as well. However, the Indian management of micronutrient security for her population has over COVID-19 times acerbated and the German loan management to nutrition and agricultural small-scale industry appears to be functioning sub-optimally.
Conclusions: Our analysis indicates both India and Germany have responded to COVID-19 in a timely and appropriate manner regarding the food and nutrition security measures. Even so not all measures employed to tackle COVID-19 food and nutrition security have been effectively implemented, It appears, that both countries are using integrated policy in their nutrition and food security response to COVID-19.
Primary Liver Cancers : Connecting the Dots of Cellular Studies and Epidemiology with Metabolomics
(2023)
Liver cancers are rising worldwide. Between molecular and epidemiological studies, a research gap has emerged which might be amenable to the technique of metabolomics. This review investigates the current understanding of liver cancer’s trends, etiology and its correlates with existing literature for hepatocellular carcinoma (HCC), cholangiocarcinoma (CCA) and hepatoblastoma (HB). Among additional factors, the literature reports dysfunction in the tricarboxylic acid metabolism, primarily for HB and HCC, and point mutations and signaling for CCA. All cases require further investigation of upstream and downstream events. All liver cancers reported dysfunction in the WNT/β-catenin and P13K/AKT/mTOR pathways as well as changes in FGFR. Metabolites of IHD1, IDH2, miRNA, purine, Q10, lipids, phosphatidylcholine, phosphatidylethanolamine, acylcarnitine, 2-HG and propionyl-CoA emerged as crucial and there was an attempt to elucidate the WNT/β-catenin and P13K/AKT/mTOR pathways metabolomically.
The development of augmented reality glasses is still ongoing and faces barriers in diffusion and concerns about their impact on users, organizations and society. The study aims to find sufficient solutions for this struggling digital innovation and to provide guidance for the implementation of augmented reality glasses in design-oriented projects. During a 3-year consortium research, acceptance and privacy have been identified as major phenomena that influence the adoption of augmented reality glasses in the logistics domain. To forge ahead digital innovation research, the focus of the presented research lies on the diffusion of this technology with design knowledge for the development of augmented reality glasses-based systems. Evidence and artifacts contribute to the still limited knowledge of system design based on augmented reality glasses from a domain-specific instantiation and an implementation framework.
Musikermedizin
(2018)
Smart Glasses haben das Potenzial, die Einarbeitungsphase von Mitarbeitern durch eine kontextsensitive Informationsversorgung und Kommunikation direkt im Blickfeld des Nutzers zu erweitern und zu verbessern. Im Rahmen eines gestaltungsorientierten Ansatzes wird das Einsatzszenario mit Hilfe von Experteninterviews analysiert und durch fachbezogene Literatur strukturiert. Als Resultat liefert dieser Beitrag spezifische Anforderungen an Smart-Glasses-basierte Assistenzsysteme in der Einarbeitungsphase von Mitarbeitern am Beispiel der Logistik-Branche aus Sicht der Praxis. Zusätzlich werden eine entsprechende Konzeption mit anschließender Evaluation eines korrespondierenden Systems sowie die dafür spezifizierten Kollaborationsfunktionen vorgestellt. Die Meta-Anforderungen, die Evaluation des vorgeschlagenen Konzeptes und die identifizierten Kollaborationsfunktionen erweitern die Wissensbasis der Wirtschaftsinformatik hinsichtlich des wenig erforschten Gestaltungswissens für Smart-Glasses-basierte Applikationen. Der Einsatz von Smart Glasses in der Einarbeitung stellt einen nutzenstiftenden Anwendungsfall für diese aktuell noch wenig verbreitete Technologie, sowie eine neue Interaktionsebene und zugehörige Kollaborationsfunktionen in der Einarbeitungsphase von Mitarbeitern dar und ist somit von hoher Relevanz sowohl für die Praxis als auch Wissenschaft.
Europe's freshwater biodiversity under climate change: distribution shifts and conservation needs
(2014)
Aim
To assess the future climatic suitability of European catchments for freshwater species and the future utility of the current network of protected areas.
Location
Europe.
Methods
Using recently updated catchment-scale species data and climate projections from multiple climate models, we assessed the climate change threat by the 2050s for 1648 European freshwater plants, fishes, molluscs, odonates, amphibians, crayfish and turtles for two dispersal scenarios and identified hotspots of change at three spatial scales: major river basins, countries and freshwater ecoregions. We considered both common species and the often overlooked rare species. To set our findings within the context of current and future conservation networks, we evaluated the coverage of freshwater biodiversity by Europe's protected area network.
Results
Six per cent of common and 77% of rare species are predicted to lose more than 90% of their current range. Eight fish species and nine mollusc species are predicted to experience 100% range loss under climate change. As the most species-rich group, molluscs are particularly vulnerable due to the high proportion of rare species and their relatively limited ability to disperse. Furthermore, around 50% of molluscs and fish species will have no protected area coverage given their projected distributions.
Main conclusions
We identified the species most at threat due to projected changes in both catchment suitability and representation within the European protected area network. Our findings suggest an urgent need for freshwater management plans to facilitate adaptation to climate change.
The conservation of freshwater ecosystems has lagged behind that of marine and terrestrial ecosystems and often requires the integration of large-scale approaches and transboundary considerations. This study aims to set the foundations of a spatial conservation strategy by identifying the most important catchments for the conservation of freshwater biodiversity in Europe.
Using data on 1296 species of fish, mollusc, odonate and aquatic plant, and the key biodiversity area criteria (species Red List status, range restriction and uniqueness of species assemblages), we identified a network of Critical Catchments for the conservation of freshwater biodiversity. Applying spatial prioritisation, we show how the prioritised network differs from the ideal case of protecting all Critical Catchments and how it changes when protected areas are included, and we also identify gaps between the prioritised network and existing protected areas.
Critical Catchments (n = 8423) covered 45% of the area of Europe, with 766 qualifying (‘trigger’) species located primarily in southern Europe. The prioritised network, limited to 17% of the area of Europe, comprised 3492 catchments mostly in southern and eastern Europe and species targets were met for at least 96% of the trigger species.
We found the majority of Critical Catchments to be inadequately covered by protected areas. However, our prioritised network presents a possible solution to augment protected areas to meet policy targets while also achieving good species coverage.
Policy implications. While Critical Catchments cover almost half of Europe, priority catchments are mostly in southern and eastern Europe where the current level of protection is not sufficient. This study presents a foundation for a Europe-wide systematic conservation plan to ensure the persistence of freshwater biodiversity. Our study provides a powerful new tool for optimising investment on the conservation of freshwater biodiversity and for meeting targets set forth in international biodiversity policies, conventions and strategies.
Climate change is expected to exacerbate the current threats to freshwater ecosystems, yet multifaceted studies on the
potential impacts of climate change on freshwater biodiversity at scales that inform management planning are lacking. The aim of this study was to fill this void through the development of a novel framework for assessing climate
change vulnerability tailored to freshwater ecosystems. The three dimensions of climate change vulnerability are as
follows: (i) exposure to climate change, (ii) sensitivity to altered environmental conditions and (iii) resilience potential.
Our vulnerability framework includes 1685 freshwater species of plants, fishes, molluscs, odonates, amphibians, crayfish and turtles alongside key features within and between catchments, such as topography and connectivity. Several
methodologies were used to combine these dimensions across a variety of future climate change models and scenarios. The resulting indices were overlaid to assess the vulnerability of European freshwater ecosystems at the catchment scale (18 783 catchments). The Balkan Lakes Ohrid and Prespa and Mediterranean islands emerge as most
vulnerable to climate change. For the 2030s, we showed a consensus among the applied methods whereby up to 573
lake and river catchments are highly vulnerable to climate change. The anthropogenic disruption of hydrological
habitat connectivity by dams is the major factor reducing climate change resilience. A gap analysis demonstrated that
the current European protected area network covers <25% of the most vulnerable catchments. Practical steps need to
be taken to ensure the persistence of freshwater biodiversity under climate change. Priority should be placed on
enhancing stakeholder cooperation at the major basin scale towards preventing further degradation of freshwater
ecosystems and maintaining connectivity among catchments. The catchments identified as most vulnerable to climate
change provide preliminary targets for development of climate change conservation management and mitigation
strategies.
The distribution of a species along a thermal gradient is commonly approximated by a unimodal response curve, with a characteristic single optimum near the tempera‐ture where a species is most likely to be found, and a decreasing probability of occur‐rence away from the optimum. We aimed at identifying thermal response curves (TRCs) of European freshwater species and evaluating the potential impact of climate warming across species, taxonomic groups, and latitude. We first applied generalized additive models using catchment‐scale global data on distribution ranges of 577 freshwater species native to Europe and four different temperature variables (the current annual mean air/water temperature and the maximum air/water temperature of the warmest month) to describe species TRCs. We then classified TRCs into one of eight curve types and identified spatial patterns in thermal responses. Finally, we in‐tegrated empirical TRCs and the projected geographic distribution of climate warm‐ing to evaluate the effect of rising temperatures on species’ distributions. For the different temperature variables, 390–463 of 577 species (67.6%–80.2%) were char‐acterized by a unimodal TRC. The number of species with a unimodal TRC decreased from central toward northern and southern Europe. Warming tolerance (WT = maxi‐mum temperature of occurrence—preferred temperature) was higher at higher lati‐tudes. Preferred temperature of many species is already exceeded. Rising temperatures will affect most Mediterranean species. We demonstrated that fresh‐water species’ occurrence probabilities are most frequently unimodal. The impact of the global climate warming on species distributions is species and latitude depend‐ent. Among the studied taxonomic groups, rising temperatures will be most detri‐mental to fish. Our findings support the efforts of catchment‐based freshwater management and conservation in the face of global warming.
Niche-based species distribution models (SDMs) have become an essential tool in conservation and restoration planning. Given the current threats to freshwater biodiversity, it is of fundamental importance to address scale effects on the performance of niche-based SDMs of freshwater species’ distributions. The scale effects are addressed here in the context of hierarchical catchment ordering, considered as counterpart to coarsening grain-size by increasing grid-cell size. We combine fish occurrence data from the Danube River Basin, the hierarchical catchment ordering and multiple environmental factors representing topographic, climatic and anthropogenic effects to model fish occurrence probability across multiple scales. We focus on 1st to 5th order catchments. The spatial scale (hierarchical catchment order) only marginally influences the mean performance of SDMs, however the uncertainty of the estimates increases with scale. Key predictors and their relative importance are scale and species dependent. Our findings have useful implications for choosing proper species dependent spatial scales for river rehabilitation measures, and for conservation planning in areas where fine grain species data are unavailable.