Open Access

Fatemeh Baghbani-Naghadehi, Susan Armijo-Olivo, Carla M. Prado, Leah Gramlich, Linda J. Woodhouse

• Background: There is an existing perception that obesity has a negative impact on complications following total knee arthroplasty (TKA). However, data on the impact of obesity levels on patient-reported outcomes (PROMs) is sparse. We investigated the association between diferent obesity classes with PROMs among patients who under went TKA. Methods: We performed retrospective secondary analyses on data extracted from the total joint replacement data repository (Alberta, Canada) managed by the Alberta Bone and Joint Health Institute (ABJHI). Patients had WOMAC and EQ5D scores measured at baseline in addition to 3 and/or 12months following TKA. Patients were stratifed according to the World Health Organization (WHO) classifcation, into fve body mass index (BMI) groups of normal, overweight, BMI class I, BMI class II, and BMI class III. The association between BMI and mean changes in WOMAC subscales (pain, function, and stifness) and EQ-5D-5L index over the time intervals of baseline to 3months and 3 to 12months following TKA was assessed. Linear mixed-efects models were used, and the models were adjusted for age, sex, length of surgery, comorbidities, year of surgery, and geographical zone where the surgery was performed.