Bone T-Scores and Functional Status: A Cross-Sectional Study on German Elderly
- Background We explore the association between bone T-scores, used in osteoporosis diagnosis, and functional status since we hypothesized that bone health can impact elderly functional status and indirectly independence. Methods In a cross-sectional study (2005–2006) on community dwelling elderly (> = 75 years) from Herne, Germany we measured bone T-scores with Dual-energy X-ray Absorptiometry, and functional status indexed by five geriatric tests: activities of daily living, instrumental activities of daily living, test of dementia, geriatric depression score and the timed-up-and-go test, and two pooled indexes: raw and standardized. Generalized linear regression was used to determine the relationship between T-scores and functional status. Results From 3243 addresses, only 632 (19%) completed a clinical visit, of which only 440 (male∶female, 243∶197) could be included in analysis. T-scores (−0.99, 95% confidence interval [CI], −1.1–0.9) predicted activities of daily living (95.3 CI, 94.5–96.2), instrumental activities of daily living (7.3 CI, 94.5–96.2), and timed-up-and-go test (10.7 CI, 10.0–11.3) (P< = 0.05). Pooled data showed that a unit improvement in T-score improved standardized pooled functional status (15 CI, 14.7–15.3) by 0.41 and the raw (99.4 CI, 97.8–101.0) by 2.27 units. These results were limited due to pooling of different scoring directions, selection bias, and a need to follow-up with evidence testing. Conclusions T-scores associated with lower functional status in community-dwelling elderly. Regular screening of osteoporosis as a preventive strategy might help maintain life quality with aging.
Author: | Shoma Barbara BerkemeyerORCiD, Jochen Schumacher, Ulrich Thiem, Ludger Pientka |
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Title (English): | Bone T-Scores and Functional Status: A Cross-Sectional Study on German Elderly |
URN: | urn:nbn:de:bsz:959-opus-37740 |
DOI: | https://doi.org/10.1371/journal.pone.0008216 |
ISSN: | 1932-6203 |
Parent Title (English): | PLoS ONE |
Document Type: | Working Paper |
Language: | English |
Year of Completion: | 2009 |
Release Date: | 2023/01/06 |
Tag: | ADL; Bone; Clinical; Cross-sectional; Dual-energy X-ray Absorptiometry; Elderly; Epidemiology; Functional Status; Geriatric depression score,; Geriatrics; IADL; Public Health; T-Scores; Test of dementia; Timed Up and Go Test |
Volume: | 4 |
Issue: | 12 |
Article Number: | e8216 |
Page Number: | 8 |
Faculties: | Fakultät AuL |
DDC classes: | 600 Technik, Medizin, angewandte Wissenschaften / 610 Medizin, Gesundheit |
Review Status: | Veröffentlichte Fassung/Verlagsversion |
Licence (German): | Creative Commons - CC BY - Namensnennung 4.0 International |