TY  - RPRT
U1  - Arbeitspapier
A1  - Berkemeyer, Shoma Barbara
A1  - Schumacher, Jochen
A1  - Thiem, Ulrich
A1  - Pientka, Ludger
T1  - Bone T-Scores and Functional Status: A Cross-Sectional Study on German Elderly
T2  - PLoS ONE
N2  - Background
We explore the association between bone T-scores, used in osteoporosis diagnosis, and functional status since we hypothesized that bone health can impact elderly functional status and indirectly independence.

Methods
In a cross-sectional study (2005–2006) on community dwelling elderly (> = 75 years) from Herne, Germany we measured bone T-scores with Dual-energy X-ray Absorptiometry, and functional status indexed by five geriatric tests: activities of daily living, instrumental activities of daily living, test of dementia, geriatric depression score and the timed-up-and-go test, and two pooled indexes: raw and standardized. Generalized linear regression was used to determine the relationship between T-scores and functional status.

Results
From 3243 addresses, only 632 (19%) completed a clinical visit, of which only 440 (male∶female, 243∶197) could be included in analysis. T-scores (−0.99, 95% confidence interval [CI], −1.1–0.9) predicted activities of daily living (95.3 CI, 94.5–96.2), instrumental activities of daily living (7.3 CI, 94.5–96.2), and timed-up-and-go test (10.7 CI, 10.0–11.3) (P< = 0.05). Pooled data showed that a unit improvement in T-score improved standardized pooled functional status (15 CI, 14.7–15.3) by 0.41 and the raw (99.4 CI, 97.8–101.0) by 2.27 units. These results were limited due to pooling of different scoring directions, selection bias, and a need to follow-up with evidence testing.

Conclusions
T-scores associated with lower functional status in community-dwelling elderly. Regular screening of osteoporosis as a preventive strategy might help maintain life quality with aging.
KW  - Clinical
KW  - Epidemiology
KW  - Elderly
KW  - Public Health
KW  - T-Scores
KW  - Bone
KW  - Geriatrics
KW  - Functional Status
KW  - Cross-sectional
KW  - Dual-energy X-ray Absorptiometry
KW  - IADL
KW  - ADL
KW  - Test of dementia
KW  - Geriatric depression score,
KW  - Timed Up and Go Test
Y1  - 2009
UN  - https://nbn-resolving.org/urn:nbn:de:bsz:959-opus-37740
SN  - 1932-6203
SS  - 1932-6203
U6  - https://doi.org/10.1371/journal.pone.0008216
DO  - https://doi.org/10.1371/journal.pone.0008216
VL  - 4
IS  - 12
SP  - 8
S1  - 8
ER  -