TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - begutachtet (reviewed) A1 - Lütke-Dörhoff, Michael A1 - Schulz, Jochen A1 - Westendarp, Heiner A1 - Visscher, Christian A1 - Wilkens, Mirja Rosemarie T1 - Dietary supplementation of 25‐hydroxycholecalciferol as an alternative to cholecalciferol in swine diets : A review JF - Journal of animal physiology and animal nutrition = Zeitschrift für Tierphysiologie, Tierernährung und Futtermittelkunde N2 - 25-hydroxycholecalciferol (25-OHD3) formed via hepatic hydroxylation from vitamin D, cholecalciferol, represents the precursor of the biologically active vitamin D hormone, 1,25-dihydroxyvitamin D. Due to a higher absorption rate and the omission of one hydroxylation, dietary supplementation of 25-OHD3 instead of vitamin D3 is considered to be more efficient as plasma concentrations of 25-OHD3 are increased more pronounced. The present review summarises studies investigating potential beneficial effects on mineral homeostasis, bone metabolism, health status and performance in sows, piglets and fattening pigs. Results are inconsistent. While most studies could not demonstrate any or only a slight impact of partial or total replacement of vitamin D3 by 25-OHD3, some experiments indicated that 25-OHD3 might alter physiological processes when animals are challenged, for example, by a restricted mineral supply. KW - 25‐hydroxycholecalciferol KW - Bone development KW - Mineral supply KW - Pig nutrition KW - Vitamin D Y1 - 2022 UN - https://nbn-resolving.org/urn:nbn:de:bsz:959-opus-55513 SN - 1439-0396 SS - 1439-0396 SN - 0931-2439 SS - 0931-2439 U6 - https://doi.org/10.1111/jpn.13768 DO - https://doi.org/10.1111/jpn.13768 VL - 106 IS - 6 SP - 1288 EP - 1305 ER -